⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10628691 | 0.97 | — | — | |
| Water SCHEMBL10628636 | 0.94 | — | — | |
| SCHEMBL10625801 | 0.89 | — | — | |
| SCHEMBL10630807 | 0.89 | — | — | |
| Hydrochloric Acid SCHEMBL7962177 | 0.84 | EPHX1 (0.35) | — | |
| Bromide SCHEMBL1394599 | 0.84 | EPHX1 (0.35) | — | |
| SCHEMBL10626682 | 0.84 | — | — | |
| SCHEMBL16288003 | 0.84 | — | — | |
| Water SCHEMBL10625822 | 0.81 | EPHX1 (0.33) | — | |
| SCHEMBL10625735 | 0.77 | EPHX1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106608892-B | Fluorine-containing water solubility platinum complex and Preparation method and use | 天津大学 | 2019-06-14 | — | — | CN | disclosed |
| CN-106608897-B | Chlorinated water dissolubility platinum complex and Preparation method and use | 天津大学 | 2019-05-31 | — | — | CN | disclosed |
| CN-106608898-B | The complex of water-soluble platinum containing deoxyglucose and Preparation method and use | 天津大学 | 2019-05-28 | — | — | CN | disclosed |
| US-20150051387-A1 | WATER SOLUBLE PLATINUM COMPLEXES FOR TUMOR TREATMENT AND PROCESS OF PREPARING SAME | GUDUI BIOPHARMA TECHNOLOGY INC. (CN) | 2015-02-19 | — | — | US | disclosed |
| US-20150011740-A1 | FLUORINE-CONTAINING WATER SOLUBLE PLATINUM COMPLEXES FOR TUMOR TREATMENT AND PROCESS OF PREPARING SAME | GUDUI BIOPHARMA TECHNOLOGY INC. (CN) | 2015-01-08 | — | — | US | disclosed |
| US-5633243-A | Anti-tumor platinum complexes, their preparation and their therapeutic use | SANKYO COMPANY, LIMITED (JP) | 1997-05-27 | — | — | US | disclosed |
| US-5527905-A | RELATIVELY FEW SIDE EFFECTS, GOOD SOLUBILITY IN WATER | SANKYO COMPANY, LIMITED (JP) | 1996-06-18 | — | — | US | disclosed |
| EP-0290280-B1 | Anti-tumor platinum complexes, their preparation and their therapeutic use | SANKYO CO (JP) | 1994-01-19 | — | — | EP | disclosed |
| EP-0296321-B1 | SYNTHESIS OF CISPLATINUM ANALOGS | AMERICAN CYANAMID COMPANY (US) | 1992-09-23 | — | — | EP | disclosed |
| US-4996337-A | Synthesis of cisplatin analogs | AMERICAN CYANAMID COMPANY (US) | 1991-02-26 | — | — | US | disclosed |
| US-4937358-A | Synthesis of cisplatin analogs | AMERICAN CYANAMID COMPANY (US) | 1990-06-26 | — | — | US | disclosed |
| US-4870070-A | ANTIEMETICS | AMERICAN CYANAMID COMPANY (US) | 1989-09-26 | — | — | US | disclosed |
| EP-0174542-B1 | CIS-PLATINUM-COMPLEXES HAVING A PENTAERYTHRITOL DERIVATIVE AS LIGAND, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL AGENT CONTAINING THESE COMPOUNDS | BEHRINGWERKE Aktiengesellschaft (DE) | 1989-06-28 | — | — | EP | disclosed |
| EP-0304566-A2 | Water soluble platinum complexes of novel malonate derivatives | AMERICAN CYANAMID COMPANY (US) | 1989-03-01 | — | — | EP | disclosed |
| US-4808730-A | Synthesis of cisplatin analogs | AMERICAN CYANAMID COMPANY (US) | 1989-02-28 | — | — | US | disclosed |
| EP-0296321-A1 | Synthesis of cisplatinum analogs | AMERICAN CYANAMID COMPANY (US) | 1988-12-28 | — | — | EP | disclosed |
| EP-0290280-A2 | Anti-tumor platinum complexes, their preparation and their therapeutic use | Sankyo Company Limited (JP) | 1988-11-09 | — | — | EP | disclosed |
| US-4730069-A | ANTITUMOR | BEHRINGWERKE AKTIENGESELLSCHAFT (DE) | 1988-03-08 | — | — | US | disclosed |
| EP-0174542-A2 | Cis-Platinum-complexes having a pentaerythritol derivative as ligand, process for their preparation and pharmaceutical agent containing these compounds | BEHRINGWERKE Aktiengesellschaft (DE) | 1986-03-19 | — | — | EP | disclosed |