Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | GRIA1 | P42261 | 3/20 | 0.41 |
| ▸ | CA1 | P00915 | 4/20 | 0.39 |
| ▸ | CA2 | P00918 | 4/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 2/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | NPY5R | Q15761 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18396950 | 0.97 | GRIA1 (0.44) | POLBALDH1A1GRIA1CA1CA2 | |
| SCHEMBL1447224 | 0.92 | — | — | |
| SCHEMBL12090531 | 0.89 | POLB (0.52) | POLBALDH1A1GRIA1CA1CA2 | |
| SCHEMBL14739265 | 0.86 | GRIA1 (0.52) | POLBALDH1A1GRIA1CA1CA2 | |
| SCHEMBL14740061 | 0.86 | GRIA1 (0.52) | POLBALDH1A1GRIA1CA1CA2 | |
| SCHEMBL14739086 | 0.86 | GRIA1 (0.52) | POLBALDH1A1GRIA1CA1CA2 | |
| SCHEMBL14740296 | 0.86 | GRIA1 (0.52) | POLBALDH1A1GRIA1CA1CA2 | |
| SCHEMBL14739515 | 0.86 | GRIA1 (0.52) | POLBALDH1A1GRIA1CA1CA2 | |
| SCHEMBL14739816 | 0.86 | GRIA1 (0.52) | POLBALDH1A1GRIA1CA1CA2 | |
| SCHEMBL14740248 | 0.86 | GRIA1 (0.52) | POLBALDH1A1GRIA1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5659065-A | CHEMICAL INTERMEDIATES FOR MEDICINAL ACTIVE AGENTS | NOVARTIS CORPORATION (US) | 1997-08-19 | — | — | US | disclosed |
| EP-0678500-A1 | Alpha-amino alkanoic acids and reduction products as intermediates in the preparation of renin inhibitors | CIBA-GEIGY AG (CH) | 1995-10-25 | — | — | EP | disclosed |