SCHEMBL890556

SCHEMBL890556

NC1CC(Cl)=NO1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10413767 0.69
SCHEMBL18677598 0.69
SCHEMBL18677599 0.69
SCHEMBL6923024 0.69
SCHEMBL13680233 0.64
SCHEMBL19526022 0.61
SCHEMBL14828375 0.51
SCHEMBL11888134 0.51
SCHEMBL125748 0.48
SCHEMBL2970008 0.48

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8426145-B2 Diagnostic method for celiac sprue THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2013-04-23 US disclosed
EP-1563300-B1 DIAGNOSTIC METHOD FOR CELIAC SPRUE UNIV LELAND STANFORD JUNIOR (US) 2012-04-18 EP disclosed
US-20120083004-A1 Diagnostic Method for Celiac Sprue THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY 2012-04-05 US disclosed
US-8071316-B2 Diagnostic method for celiac sprue THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2011-12-06 US disclosed
US-20100317025-A1 Diagnostic Method for Celiac Sprue THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY 2010-12-16 US disclosed
US-7776545-B2 Diagnostic method for Celiac Sprue THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2010-08-17 US disclosed
US-20090312260-A1 DRUG THERAPY FOR CELIAC SPRUE THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY 2009-12-17 US disclosed
US-7605150-B2 Drug therapy for Celiac Sprue THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2009-10-20 US disclosed
US-7563864-B2 Prolyl endopeptidase mediated destruction of T cell epitopes in whole gluten CELIAC SPRUE RESEARCH FOUNDATION (US) 2009-07-21 US disclosed
EP-1507549-A4 DRUG THERAPY FOR CELIAC SPRUE UNIV LELAND STANFORD JUNIOR (US) 2009-07-01 EP disclosed
US-20060286601-A1 Prolyl endopeptidase mediated destruction of T cell epitopes in whole gluten CELIAC SPRUE RESEARCH FOUNDATION 2006-12-21 US disclosed
US-20060240475-A1 Diagnostic method for celiac sprue NATIONAL SCIENCE FOUNDATION 2006-10-26 US disclosed
US-20060035838-A1 Drug therapy for celiac sprue THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY 2006-02-16 US disclosed
EP-1563300-A2 DIAGNOSTIC METHOD FOR CELIAC SPRUE The Board of Trustees of The Leland Stanford Junior University (US) 2005-08-17 EP disclosed
EP-1507549-A2 DRUG THERAPY FOR CELIAC SPRUE The Board of Trustees of The Leland Stanford Junior University (US) 2005-02-23 EP disclosed
WO-2004045392-A2 DIAGNOSTIC METHOD FOR CELIAC SPRUE THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2004-06-03 WO disclosed
WO-2003096979-A2 DRUG THERAPY FOR CELIAC SPRUE THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2003-11-27 WO disclosed