SCHEMBL8905893

SCHEMBL8905893

C1=NC2=Nc3ccccc3C2=C1

nearest known ligand 0.37

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30168823 1.00 IDO1 (0.33) IDO1
SCHEMBL27840600 0.98 IDO1 (0.32) IDO1
Glyoxylate SCHEMBL2364947 0.85 IDO1 (0.33) IDO1
SCHEMBL29941302 0.85 MEN1 (0.39)
SCHEMBL29352286 0.75 MAPT (0.40) IDO1
SCHEMBL1120300 0.75 MAPT (0.40) IDO1
SCHEMBL3226013 0.73 IDO1 (0.37) IDO1
SCHEMBL27849362 0.68 IDO1 (0.34) IDO1
SCHEMBL28942884 0.68 IDO1 (0.32) IDO1
SCHEMBL28439324 0.67 IDO1 (0.31) IDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105601633-A Catalytic synthetic method of pyrrolindole compounds LI NAIWEN 2016-05-25 CN disclosed
CN-105218553-A A kind of synthetic method of pharmaceutical intermediate pyrrolo-indole compounds LI NAIWEN 2016-01-06 CN disclosed
CN-102796107-A Method for synthesizing pyrrol[2,3-b]indole compounds KUNMING INST BOTANY CN ACAD 2012-11-28 CN disclosed
CN-102796107-A Method for synthesizing pyrrol[2,3-b]indole compounds KUNMING INST BOTANY CN ACAD 2012-11-28 CN disclosed
EP-0538314-B1 INDANO PYRROLIDINE CARBAMATES PFIZER (US) 1997-06-18 EP disclosed