Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 3/20 | 0.55 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | CDYL | Q9Y232 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19665869 | 0.84 | NPSR1 (0.43) | L3MBTL1CYP2C19NPSR1 | |
| SCHEMBL27489439 | 0.83 | CYP4F2 (0.40) | CYP4F2CYP4A11ALDH1A1SMN1; SMN2POLB | |
| SCHEMBL10981821 | 0.82 | CYP4F2 (0.65) | CYP4F2CYP4A11ALDH1A1GAASMN1; SMN2 | |
| SCHEMBL27753784 | 0.82 | CYP4F2 (0.40) | CYP4F2CYP4A11ALDH1A1GAASMN1; SMN2 | |
| SCHEMBL10787806 | 0.79 | HDAC3 (0.41) | SMN1; SMN2L3MBTL1MAPTMAPK1NPSR1 | |
| SCHEMBL7376639 | 0.79 | CYP4F2 (0.43) | CYP4F2CYP4A11ALDH1A1SMN1; SMN2POLB | |
| SCHEMBL21008087 | 0.78 | CYP4F2 (0.55) | CYP4F2CYP4A11SMN1; SMN2EPHX2ALOX5 | |
| SCHEMBL10723055 | 0.77 | CYP4F2 (0.58) | CYP4F2CYP4A11ALDH1A1GAASMN1; SMN2 | |
| SCHEMBL28497564 | 0.77 | TSHR (0.54) | ALDH1A1GAASMN1; SMN2MAPTLMNA | |
| SCHEMBL27477309 | 0.77 | RAD52 (0.40) | ALDH1A1L3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0805816-A1 | COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES | NOVO NORDISK A/S (DK) | 1997-11-12 | — | — | EP | disclosed |
| WO-1996022997-A1 | COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES | NOVO NORDISK A/S (DK) | 1996-08-01 | — | — | WO | disclosed |