Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.42 |
| ▸ | HTRA1 | Q92743 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.37 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6319198 | 1.00 | POLB (0.57) | POLBCYP1A2CYP3A4CYP2C19CHRM2 | |
| SCHEMBL6321596 | 1.00 | POLB (0.57) | POLBCYP1A2CYP3A4CYP2C19CHRM2 | |
| SCHEMBL24441127 | 0.87 | POLB (0.58) | POLBCYP1A2CYP3A4CYP2C19CHRM2 | |
| SCHEMBL29044251 | 0.87 | POLB (0.58) | POLBCYP1A2CYP3A4CYP2C19CHRM2 | |
| SCHEMBL29044252 | 0.87 | POLB (0.58) | POLBCYP1A2CYP3A4CYP2C19CHRM2 | |
| SCHEMBL23897273 | 0.86 | POLB (0.53) | POLBCYP1A2CYP3A4CYP2C19CHRM2 | |
| SCHEMBL23881175 | 0.86 | POLB (0.53) | POLBCYP1A2CYP3A4CYP2C19CHRM2 | |
| SCHEMBL23881172 | 0.86 | POLB (0.53) | POLBCYP1A2CYP3A4CYP2C19CHRM2 | |
| SCHEMBL23881173 | 0.86 | POLB (0.53) | POLBCYP1A2CYP3A4CYP2C19CHRM2 | |
| SCHEMBL7391429 | 0.86 | POLB (0.44) | POLBCYP1A2CYP3A4CYP2C19CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5629406-A | AMINO ACID DERIVATIVES | SANKYO COMPANY, LIMITED (JP) | 1997-05-13 | — | — | US | disclosed |