Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP26A1 | O43174 | 2/20 | 0.69 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.69 |
| ▸ | CYP26B1 | Q9NR63 | 2/20 | 0.69 |
| ▸ | RARG | P13631 | 8/20 | 0.48 |
| ▸ | RXRA | P19793 | 5/20 | 0.47 |
| ▸ | RARA | P10276 | 6/20 | 0.47 |
| ▸ | RARB | P10826 | 6/20 | 0.47 |
| ▸ | RXRB | P28702 | 2/20 | 0.45 |
| ▸ | PPARG | P37231 | 3/20 | 0.43 |
| ▸ | RXRG | P48443 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5084218 | 0.90 | CYP26A1 (0.67) | CYP26A1CYP3A4CYP26B1RARGRXRA | |
| SCHEMBL9271838 | 0.87 | CYP26A1 (0.64) | CYP26A1CYP3A4CYP26B1RARGRXRA | |
| SCHEMBL5084224 | 0.87 | CYP26A1 (0.72) | CYP26A1CYP3A4CYP26B1RARGRXRA | |
| SCHEMBL9189823 | 0.85 | CYP26A1 (0.54) | CYP26A1CYP3A4CYP26B1RARGRXRA | |
| SCHEMBL8461581 | 0.82 | CYP26A1 (1.00) | CYP26A1CYP3A4CYP26B1RARGRXRA | |
| SCHEMBL5084222 | 0.81 | CYP3A4 (0.63) | CYP26A1CYP3A4CYP26B1RARGRXRA | |
| SCHEMBL9194990 | 0.80 | RARG (0.52) | CYP26A1CYP3A4CYP26B1RARGRXRA | |
| SCHEMBL9193673 | 0.80 | CYP26A1 (0.62) | CYP26A1CYP3A4CYP26B1RARGRXRA | |
| SCHEMBL8908988 | 0.80 | CYP3A4 (0.64) | CYP26A1CYP3A4CYP26B1RARGRXRA | |
| SCHEMBL9191684 | 0.79 | CYP26A1 (0.73) | CYP26A1CYP3A4CYP26B1RARGRXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0514264-B1 | Biaromatic compounds derived from compounds having a salicylic configuration, their preparation process and their use in human and veterinary medicine and in cosmetics | CIRD GALDERMA (FR) | 1995-11-15 | — | — | EP | claimed |
| US-5654331-A | SKIN AND RESPIRATORY SYSTEM DISORDERS; ANTIINFLAMMATORY AGENTS; ANTIALLERGENS | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (CIRD GALDERMA) (FR) | 1997-08-05 | — | — | US | disclosed |
| US-5476860-A | Diaromatic compounds derived from a salicylic unit and their use in human and veterinary medicine and in cosmetics | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES (CIRD GALDERMA) (FR) | 1995-12-19 | — | — | US | disclosed |