Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.57 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | SQLE | Q14534 | 3/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | PDE4A | P27815 | 1/20 | 0.37 |
| ▸ | SNCA | P37840 | 1/20 | 0.37 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8978515 | 0.96 | KDM1A (0.63) | KDM1APTPN1KDM4ESQLEKMT2A | |
| SCHEMBL8978511 | 0.96 | KDM1A (0.63) | KDM1APTPN1KDM4ESQLEKMT2A | |
| SCHEMBL8978484 | 0.93 | PTPN1 (0.67) | KDM1APTPN1PTGS1PDE4ASNCA | |
| SCHEMBL8978488 | 0.93 | PTPN1 (0.67) | KDM1APTPN1PTGS1PDE4ASNCA | |
| SCHEMBL27785652 | 0.90 | KDM1A (0.62) | KDM1APTPN1SQLEPTGS1PDE4A | |
| SCHEMBL8978492 | 0.88 | PTPN1 (0.65) | KDM1APTPN1PTGS1PDE4ASNCA | |
| SCHEMBL8978494 | 0.88 | PTPN1 (0.65) | KDM1APTPN1PTGS1PDE4ASNCA | |
| SCHEMBL1658397 | 0.84 | KDM1A (0.41) | KDM1APTPN1KDM4ESQLEKMT2A | |
| SCHEMBL1658396 | 0.84 | KDM1A (0.41) | KDM1APTPN1KDM4ESQLEKMT2A | |
| SCHEMBL889883 | 0.84 | SQLE (0.55) | KDM1APTPN1KDM4ESQLEKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5600015-A | USING RUTHENIUM COMPLEX OF OPTICALLY ACTIVE ATROPISOMERIC DIPHOSPHINE LIGAND AS HYDROGENATION CATALYST | HOFFMANN-LA ROCHE INC. (US) | 1997-02-04 | — | — | US | disclosed |
| EP-0565975-B1 | Process for the preparation of isoprenoid derivatives | HOFFMANN LA ROCHE (CH) | 1996-09-04 | — | — | EP | disclosed |
| EP-0565975-A2 | Process for the preparation of isoprenoid derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1993-10-20 | — | — | EP | disclosed |