Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.42 |
| ▸ | CYP26B1 | Q9NR63 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | RARA | P10276 | 4/20 | 0.38 |
| ▸ | RARB | P10826 | 4/20 | 0.38 |
| ▸ | RARG | P13631 | 4/20 | 0.38 |
| ▸ | RXRA | P19793 | 2/20 | 0.38 |
| ▸ | RXRB | P28702 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9191681 | 0.88 | CYP26A1 (0.48) | CYP3A4CYP26A1CYP26B1RARARARB | |
| SCHEMBL8907801 | 0.87 | CYP26A1 (0.45) | TDP1CYP3A4CYP26A1CYP26B1MAOB | |
| SCHEMBL8907823 | 0.83 | CYP3A4 (0.60) | TDP1CYP3A4CYP26A1CYP26B1MAOB | |
| SCHEMBL8907780 | 0.82 | CYP3A4 (0.47) | TDP1CYP3A4CYP26A1CYP26B1MAOB | |
| SCHEMBL8909342 | 0.82 | CYP3A4 (0.43) | TDP1CYP3A4CYP26A1CYP26B1MAOB | |
| SCHEMBL8839385 | 0.81 | TDP1 (0.50) | TDP1CYP3A4MAOBALDH1A1RXRA | |
| SCHEMBL9263958 | 0.79 | MAOB (0.51) | TDP1CYP3A4CYP26A1CYP26B1MAOB | |
| SCHEMBL8907526 | 0.78 | CYP3A4 (0.43) | TDP1CYP3A4CYP26A1CYP26B1MAOB | |
| SCHEMBL8839372 | 0.76 | TDP1 (0.46) | TDP1CYP3A4CYP26A1CYP26B1MAOB | |
| SCHEMBL8907584 | 0.75 | CYP3A4 (0.61) | TDP1CYP3A4CYP26A1CYP26B1MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5654331-A | SKIN AND RESPIRATORY SYSTEM DISORDERS; ANTIINFLAMMATORY AGENTS; ANTIALLERGENS | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (CIRD GALDERMA) (FR) | 1997-08-05 | — | — | US | disclosed |
| US-5476860-A | Diaromatic compounds derived from a salicylic unit and their use in human and veterinary medicine and in cosmetics | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES (CIRD GALDERMA) (FR) | 1995-12-19 | — | — | US | disclosed |