Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28847957 | 0.76 | TSHR (0.32) | TSHRTDP1ALDH1A1 | |
| SCHEMBL159716 | 0.71 | — | — | |
| SCHEMBL17966582 | 0.71 | TSHR (0.38) | TSHRTDP1ALDH1A1 | |
| SCHEMBL523016 | 0.71 | — | — | |
| SCHEMBL6359432 | 0.69 | — | — | |
| SCHEMBL1220821 | 0.67 | — | — | |
| SCHEMBL8170204 | 0.67 | TSHR (0.40) | TSHRTDP1ALDH1A1 | |
| Ammonia Solution, Strong SCHEMBL16628515 | 0.65 | — | — | |
| SCHEMBL11240073 | 0.65 | — | — | |
| SCHEMBL2273487 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5624680-A | SKIN ABSORPTION OF DRUGS WITH POLYETHERSILOXANE BLOCK COPOLYMERS | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1997-04-29 | — | — | US | disclosed |
| US-5589586-A | Nucleosides attached to a solid support through a 3'-silyl linkage and their use in oligonucleotide synthesis | PHARMACIA LKB BIOTECHNOLOGY AB (SE) | 1996-12-31 | — | — | US | disclosed |
| EP-0710688-A1 | HYDROXYSILYL-TERMINATED POLYOXYETHYLENE COMPOUND, QUATERNARY-SALT-TERMINATED BLOCK COPOLYMER, AND PERCUTANEOUS ABSORPTION PROMOTER | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1996-05-08 | — | — | EP | disclosed |
| EP-0514513-B1 | METHOD AND MEANS FOR OLIGONUCLEOTIDE SYNTHESIS | PHARMACIA BIOTECH AB (SE) | 1996-01-31 | — | — | EP | disclosed |
| EP-0514513-A1 | METHOD AND MEANS FOR OLIGONUCLEOTIDE SYNTHESIS. | PHARMACIA LKB BIOTECH (SE) | 1992-11-25 | — | — | EP | disclosed |
| WO-1992009615-A1 | METHOD AND MEANS FOR OLIGONUCLEOTIDE SYNTHESIS | PHARMACIA LKB BIOTECHNOLOGY AB (SE) | 1992-06-11 | — | — | WO | disclosed |