Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.35 |
| ▸ | MMP1 | P03956 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | MMP3 | P08254 | 1/20 | 0.32 |
| ▸ | MMP9 | P14780 | 1/20 | 0.32 |
| ▸ | MMP13 | P45452 | 1/20 | 0.32 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31751606 | 0.79 | TDP1 (0.33) | TDP1SMN1; SMN2SLC22A6 | |
| SCHEMBL4600025 | 0.79 | TDP1 (0.33) | TDP1SMN1; SMN2SLC22A6 | |
| SCHEMBL10476486 | 0.79 | SMN1; SMN2 (0.43) | TDP1SMN1; SMN2 | |
| SCHEMBL880674 | 0.74 | MAPT (0.38) | SMN1; SMN2MAPTALDH1A1LMNA | |
| SCHEMBL8920591 | 0.74 | TDP1 (0.36) | TDP1SMN1; SMN2SLC22A6MMP1MMP2 | |
| SCHEMBL10212 | 0.73 | TDP1 (0.43) | TDP1SMN1; SMN2SLC22A6FOLH1ALOX15 | |
| SCHEMBL2593546 | 0.73 | TDP1 (0.43) | TDP1SMN1; SMN2SLC22A6FOLH1ALOX15 | |
| SCHEMBL2580759 | 0.73 | TDP1 (0.43) | TDP1SMN1; SMN2SLC22A6FOLH1ALOX15 | |
| SCHEMBL30293 | 0.72 | TDP1 (0.48) | TDP1SMN1; SMN2SLC22A6FOLH1ALOX15 | |
| SCHEMBL5157972 | 0.72 | TDP1 (0.48) | TDP1SMN1; SMN2SLC22A6FOLH1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5637255-A | OPTICALLY ACTIVE FORM, USED FOR OPTICAL OR ELECTROOPTICAL DISPLYING; HIGH TWISTING; DOPANT | ROLIC AG (CH) | 1997-06-10 | — | — | US | disclosed |