Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 4/20 | 0.41 |
| ▸ | CA1 | P00915 | 4/20 | 0.41 |
| ▸ | CA9 | Q16790 | 4/20 | 0.41 |
| ▸ | PREP | P48147 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7257408 | 0.91 | CA12 (0.40) | CA12CA1CA9PREP | |
| SCHEMBL8907638 | 0.87 | CA12 (0.40) | CA12CA1CA9PREP | |
| SCHEMBL23064445 | 0.80 | CA12 (0.44) | CA12CA1CA9PREP | |
| SCHEMBL6768684 | 0.80 | CA12 (0.44) | CA12CA1CA9PREP | |
| SCHEMBL2292629 | 0.80 | CA12 (0.44) | CA12CA1CA9PREP | |
| SCHEMBL4978286 | 0.80 | CA12 (0.44) | CA12CA1CA9PREP | |
| SCHEMBL9013390 | 0.80 | CA12 (0.44) | CA12CA1CA9PREP | |
| SCHEMBL8907783 | 0.78 | CA12 (0.42) | CA12CA1CA9PREP | |
| SCHEMBL7258416 | 0.78 | TYR (0.40) | CA12CA1CA9PREP | |
| SCHEMBL17621250 | 0.78 | CA12 (0.43) | CA12CA1CA9PREP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5686478-A | Endothelin antagonists | MERCK & CO. INC. (US) | 1997-11-11 | — | — | US | disclosed |
| WO-1995003295-A1 | ENDOTHELIN ANTAGONISTS | MERCK & CO., INC. (US) | 1995-02-02 | — | — | WO | disclosed |