Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 13/20 | 0.66 |
| ▸ | SRD5A1 | P18405 | 5/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8585490 | 1.00 | SRD5A2 (0.66) | SRD5A2SRD5A1 | |
| SCHEMBL8907905 | 1.00 | SRD5A2 (0.66) | SRD5A2SRD5A1 | |
| SCHEMBL8908576 | 0.93 | SRD5A2 (0.64) | SRD5A2SRD5A1 | |
| SCHEMBL8907848 | 0.92 | SRD5A2 (0.63) | SRD5A2SRD5A1 | |
| SCHEMBL8909300 | 0.92 | SRD5A2 (0.63) | SRD5A2SRD5A1 | |
| SCHEMBL9116904 | 0.92 | SRD5A2 (0.62) | SRD5A2SRD5A1 | |
| SCHEMBL8907918 | 0.92 | SRD5A2 (0.68) | SRD5A2SRD5A1 | |
| SCHEMBL8908454 | 0.91 | SRD5A2 (0.58) | SRD5A2SRD5A1 | |
| SCHEMBL8909603 | 0.91 | SRD5A2 (0.61) | SRD5A2SRD5A1 | |
| SCHEMBL8909283 | 0.89 | SRD5A2 (0.53) | SRD5A2SRD5A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5641765-A | TREATS PROSTATIC ADENOCARCINOMA, BENIGN PROSTATE HYPERTROPHY; ANTAGONSIT, ANTAGONISM | SMITHKLINE BEECHAM CORPORATION (US) | 1997-06-24 | — | — | US | disclosed |
| US-5641877-A | 17-α and 17-β substituted acyl-3-carboxy-3, 5-dienes and use in inhibiting 5-α-reductase | SMITHKLINE BEECHAM CORPORATION (US) | 1997-06-24 | — | — | US | disclosed |