Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.41 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.41 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.35 |
| ▸ | KDM5A | P29375 | 7/20 | 0.35 |
| ▸ | KDM4C | Q9H3R0 | 6/20 | 0.35 |
| ▸ | PHF8 | Q9UPP1 | 4/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | KDM5C | P41229 | 1/20 | 0.33 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.33 |
| ▸ | KDM4A | O75164 | 1/20 | 0.32 |
| ▸ | GBA1 | P04062 | 1/20 | 0.32 |
| ▸ | NOS3 | P29474 | 1/20 | 0.31 |
| ▸ | NOS1 | P29475 | 1/20 | 0.31 |
| ▸ | NOS2 | P35228 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28905825 | 0.83 | CA12 (0.42) | SPHK2SPHK1DNM1CA12CA1 | |
| SCHEMBL8499444 | 0.83 | CA12 (0.42) | SPHK2SPHK1DNM1CA12CA1 | |
| SCHEMBL2954535 | 0.83 | CA12 (0.42) | SPHK2SPHK1DNM1CA12CA1 | |
| SCHEMBL8498288 | 0.83 | CA12 (0.42) | SPHK2SPHK1DNM1CA12CA1 | |
| SCHEMBL8495268 | 0.83 | CA12 (0.42) | SPHK2SPHK1DNM1CA12CA1 | |
| Hydrochloric Acid SCHEMBL4483541 | 0.81 | CA12 (0.41) | SPHK2SPHK1DNM1CA12CA1 | |
| SCHEMBL28841120 | 0.81 | SPHK1 (0.41) | SPHK2SPHK1DNM1CA12CA1 | |
| Hydrochloric Acid SCHEMBL19371460 | 0.81 | CA12 (0.41) | SPHK2SPHK1DNM1CA12CA1 | |
| SCHEMBL28415126 | 0.81 | CA12 (0.41) | SPHK2SPHK1DNM1KDM5APHF8 | |
| SCHEMBL28417961 | 0.81 | CA12 (0.41) | SPHK2SPHK1DNM1KDM5APHF8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0508381-B1 | Liquid composition for contact lenses and method for cleaning a contact lens | TOMEI SANGYO KK (JP) | 1997-09-03 | — | — | EP | disclosed |
| US-5281277-A | Glycerol, boric acid or borate, protease | TOMEI SANGYO KABUSHIKI KAISHA (JP) | 1994-01-25 | — | — | US | disclosed |
| EP-0508381-A2 | Liquid composition for contact lenses and method for cleaning a contact lens | Tomei Sangyo Kabushiki Kaisha (JP) | 1992-10-14 | — | — | EP | disclosed |