Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | APP | P05067 | 3/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | PLAU | P00749 | 1/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | REN | P00797 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | LTA4H | P09960 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8896223 | 0.96 | HTT (0.40) | HTTAPPTDP1NPC1RAB9A | |
| SCHEMBL8910006 | 0.96 | HTT (0.40) | HTTAPPTDP1NPC1RAB9A | |
| SCHEMBL8910126 | 0.95 | HTT (0.39) | HTTAPPTDP1NPC1RAB9A | |
| SCHEMBL8407941 | 0.89 | HTT (0.43) | HTTTDP1ALDH1A1 | |
| SCHEMBL8657700 | 0.86 | HTT (0.40) | HTTNPC1RAB9APLAUALDH1A1 | |
| SCHEMBL8408726 | 0.85 | HTT (0.42) | HTTRAB9AALDH1A1KMT2A | |
| SCHEMBL8405697 | 0.85 | HTT (0.42) | HTTALDH1A1KMT2A | |
| SCHEMBL6550042 | 0.84 | HTT (0.42) | HTTTDP1RAB9AALDH1A1MAPT | |
| SCHEMBL8659377 | 0.83 | HTT (0.43) | HTTNPC1ALDH1A1MAPTKMT2A | |
| SCHEMBL13528419 | 0.83 | HTT (0.43) | HTTTDP1NPC1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997027173-A2 | DIHALOPROPENE COMPOUNDS, THEIR USE AS INSECTICIDES/ACARICIDES AND INTERMEDIATES FOR THEIR PRODUCTION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-31 | — | — | WO | disclosed |