Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.75 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.69 |
| ▸ | TSHR | P16473 | 2/20 | 0.69 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.69 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.69 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.69 |
| ▸ | THPO | P40225 | 1/20 | 0.69 |
| ▸ | LMNA | P02545 | 1/20 | 0.68 |
| ▸ | TP53 | P04637 | 1/20 | 0.68 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.68 |
| ▸ | HTT | P42858 | 1/20 | 0.68 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.68 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6262868 | 1.00 | SLC29A1 (0.75) | SLC29A1ADORA1TSHRADORA3ADORA2A | |
| SCHEMBL8820463 | 0.90 | SLC29A1 (0.71) | SLC29A1ADORA1TSHRADORA3ADORA2A | |
| SCHEMBL6758909 | 0.89 | SLC29A1 (0.86) | SLC29A1ADORA1TSHRADORA3ADORA2A | |
| SCHEMBL20626332 | 0.89 | SLC29A1 (0.86) | SLC29A1ADORA1TSHRADORA3ADORA2A | |
| SCHEMBL14713238 | 0.89 | SLC29A1 (0.86) | SLC29A1ADORA1TSHRADORA3ADORA2A | |
| SCHEMBL17470300 | 0.88 | SLC29A1 (0.79) | SLC29A1ADORA1TSHRADORA3ADORA2A | |
| SCHEMBL20579787 | 0.88 | SLC29A1 (0.79) | SLC29A1ADORA1TSHRADORA3ADORA2A | |
| SCHEMBL29364428 | 0.88 | SLC29A1 (0.79) | SLC29A1ADORA1TSHRADORA3ADORA2A | |
| SCHEMBL899687 | 0.88 | SLC29A1 (0.79) | SLC29A1ADORA1TSHRADORA3ADORA2A | |
| SCHEMBL16010153 | 0.88 | SLC29A1 (0.79) | SLC29A1ADORA1TSHRADORA3ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0603348-A1 | PURINE DERIVATIVES | NOVO NORDISK A/S (DK) | 1994-06-29 | — | — | EP | claimed |
| WO-1993023418-A1 | PURINE DERIVATIVES | NOVO NORDISK A/S (DK) | 1993-11-25 | — | — | WO | claimed |
| US-5672588-A | Purine derivatives | NOVO NORDISK A/S (DK) | 1997-09-30 | — | — | US | disclosed |
| EP-0603348-A1 | PURINE DERIVATIVES | NOVO NORDISK A/S (DK) | 1994-06-29 | — | — | EP | disclosed |
| WO-1993023418-A1 | PURINE DERIVATIVES | NOVO NORDISK A/S (DK) | 1993-11-25 | — | — | WO | disclosed |