SCHEMBL891002

SCHEMBL891002

OC1CCC(Oc2ccc(Sc3ccc(OC4CCC(O)CC4)cc3)cc2)CC1

nearest known ligand 0.51

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.51
PARP10 Q53GL7 1/20 0.40
CHEK2 O96017 1/20 0.39
HRH3 Q9Y5N1 2/20 0.38
GAA P10253 1/20 0.36
HRH1 P35367 2/20 0.36
DHFR P00374 1/20 0.36
EPHX2 P34913 3/20 0.36
ALDH1A1 P00352 1/20 0.35
TSHR P16473 1/20 0.35
MAP4K4 O95819 1/20 0.35
FURIN P09958 2/20 0.34
NR1H2 P55055 1/20 0.33
PTPN1 P18031 1/20 0.33
FDPS P14324 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13724423 0.80 PARP10 (0.46) PARP10CHEK2HRH3HRH1EPHX2
SCHEMBL18058688 0.80 SMN1; SMN2 (0.54) SMN1; SMN2PARP10HRH3GAAHRH1
SCHEMBL9774780 0.78 EPHX2 (0.54) EPHX2
SCHEMBL8574918 0.78 HRH3 (0.42) PARP10CHEK2HRH3HRH1EPHX2
SCHEMBL2018301 0.78 EPHX2 (0.47) PARP10CHEK2HRH3HRH1EPHX2
SCHEMBL12544887 0.78 HRH1 (0.59) SMN1; SMN2PARP10HRH1EPHX2
SCHEMBL22816267 0.77 ESR2 (0.57) PARP10CHEK2HRH3HRH1ALDH1A1
SCHEMBL24799517 0.76 PARP10 (0.54) PARP10CHEK2EPHX2ALDH1A1MAP4K4
SCHEMBL16195543 0.76 SMN1; SMN2 (0.67) SMN1; SMN2PARP10GAAHRH1DHFR
SCHEMBL14634351 0.74 EPHX2 (0.41) PARP10CHEK2HRH3HRH1EPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 193 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12384870-B2 Method for setting polymerization condition and method for manufacturing optical material MITSUI CHEMICALS, INC. (JP) 2025-08-12 US disclosed
US-12275813-B2 Polymerizable composition for optical materials and application of same MITSUI CHEMICALS, INC. (JP) 2025-04-15 US disclosed
EP-3308928-B1 METHOD FOR PRODUCING PLASTIC LENS AND USE OF A DEVICE FOR PRODUCING A PLASTIC LENS MITSUI CHEMICALS INC (JP) 2025-03-05 EP disclosed
EP-3521907-B1 PHOTOCHROMIC LENS AND POLYMERIZABLE COMPOSITION MITSUI CHEMICALS INC (JP) 2024-12-04 EP disclosed
EP-3527597-B1 POLYMERIZABLE COMPOSITION FOR OPTICAL MATERIAL, AND USE THEREOF MITSUI CHEMICALS INC (JP) 2024-08-07 EP disclosed
US-12054568-B2 Optical material composition and optical material TOKUYAMA CORPORATION (JP) 2024-08-06 US disclosed
EP-3643735-B1 PHOTOCHROMIC POLYROTAXANE COMPOUND, AND CURABLE COMPOSITION CONTAINING SAID PHOTOCHROMIC POLYROTAXANE COMPOUND TOKUYAMA CORP (JP) 2024-07-31 EP disclosed
CN-110869355-B Benzopyran compound, curable composition containing the compound, and optical article containing cured product formed from the curable composition 株式会社德山 2023-11-14 CN disclosed
CN-112424260-B Photochromic compound and curable composition containing the same 株式会社德山 2023-10-13 CN disclosed
US-11767467-B2 Photochromic compound and curable composition containing said photochromic compound TOKUYAMA CORPORATION (JP) 2023-09-26 US disclosed
EP-0630927-A2 Optical urethane resin Takeda Chemical Industries, Ltd. (JP) 1994-12-28 EP disclosed
EP-0329389-B1 Polyurethane base lens and its preparation method MITSUI TOATSU CHEMICALS (JP) 1994-11-02 EP disclosed
EP-0351073-B1 Lens comprising a resin having a large refractive index and process for preparing the lens MITSUI TOATSU CHEMICALS (JP) 1994-09-21 EP disclosed
EP-0553801-A1 Use of sulfur-containing acid phosphoric ester as internal release agent MITSUI TOATSU CHEMICALS, Inc. (JP) 1993-08-04 EP disclosed
US-5084545-A Polythiourethanes for impact strength, lightweight lenses MITSUI TOATSU CHEMICALS, INC. (JP) 1992-01-28 US disclosed
US-4929707-A Polyurethane base lens resin, plastic lens comprising the resin and preparation method of the lens MITSUI TOATSU CHEMICALS, INC. (JP) 1990-05-29 US disclosed
CN-1039429-A Resin having high refractive index, lens comprising the resin, and method for producing the lens MITSUI TOATSU CHEMICALS (JP) 1990-02-07 CN disclosed
EP-0351073-A2 Lens comprising a resin having a large refractive index and process for preparing the lens MITSUI TOATSU CHEMICALS, Inc. (JP) 1990-01-17 EP disclosed
CN-1035520-A Polyurethane-based resin for lens production, plastic lens comprising the resin, and method for producing the lens MITSUI TOATSU CHEMICALS ICOR (JP) 1989-09-13 CN disclosed
EP-0329389-A2 Polyurethane base lens and its preparation method MITSUI TOATSU CHEMICALS, Inc. (JP) 1989-08-23 EP disclosed