Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 1/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.40 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.40 |
| ▸ | MYC | P01106 | 1/20 | 0.39 |
| ▸ | WDR5 | P61964 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | ANPEP | P15144 | 1/20 | 0.39 |
| ▸ | MME | P08473 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | ADAMTS4 | O75173 | 2/20 | 0.37 |
| ▸ | MMP13 | P45452 | 2/20 | 0.37 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8813467 | 0.90 | FFAR1 (0.44) | ABL1FFAR1AKR1B1MYCWDR5 | |
| SCHEMBL8065614 | 0.89 | MYC (0.45) | FFAR1AKR1B1MYCWDR5PTPN1 | |
| SCHEMBL2432 | 0.89 | MYC (0.45) | FFAR1AKR1B1MYCWDR5PTPN1 | |
| SCHEMBL2174 | 0.89 | MYC (0.45) | FFAR1AKR1B1MYCWDR5PTPN1 | |
| Hydrochloric Acid SCHEMBL3526296 | 0.88 | MYC (0.45) | FFAR1AKR1B1MYCWDR5ALDH1A1 | |
| Hydrochloric Acid SCHEMBL15663201 | 0.88 | MYC (0.45) | FFAR1AKR1B1MYCWDR5ALDH1A1 | |
| Oxalic Acid SCHEMBL1616541 | 0.86 | MME (0.44) | FFAR1AKR1B1MYCWDR5PTPN1 | |
| SCHEMBL3121 | 0.80 | MYC (0.43) | FFAR1AKR1B1MYCWDR5ALDH1A1 | |
| SCHEMBL2465 | 0.80 | MYC (0.43) | FFAR1AKR1B1MYCWDR5ALDH1A1 | |
| SCHEMBL14004740 | 0.79 | FFAR1 (0.48) | FFAR1AKR1B1MYCWDR5PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5620998-A | CARDIOVASCULAR DISORDERS; HYPOTENSIVE AGENTS | CIBA-GEIGY CORPORATION (US) | 1997-04-15 | — | — | US | disclosed |
| US-5506240-A | HYPOTENSIVE AGENTS | CIBA-GEIGY CORPORATION (US) | 1996-04-09 | — | — | US | disclosed |