⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10617016 | 0.78 | — | — | |
| SCHEMBL200454 | 0.78 | — | — | |
| SCHEMBL4461167 | 0.78 | — | — | |
| SCHEMBL27371614 | 0.75 | — | — | |
| SCHEMBL11764980 | 0.75 | CTSC (0.34) | — | |
| SCHEMBL27400165 | 0.73 | — | — | |
| SCHEMBL9176456 | 0.72 | DPP4 (0.44) | — | |
| SCHEMBL9177735 | 0.72 | DPP4 (0.44) | — | |
| SCHEMBL21724388 | 0.72 | HDAC3 (0.41) | — | |
| SCHEMBL2027143 | 0.70 | PTGS1 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 237 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4212546-A1 | METHODS OF PRODUCING LONG ACTING CTP-MODIFIED POLYPEPTIDES | OPKO Biologics Ltd. (IL) | 2023-07-19 | — | — | EP | disclosed |
| US-20220170005-A1 | LONG-ACTING COAGULATION FACTORS AND METHODS OF PRODUCING SAME | OPKO BIOLOGICS LTD. (IL) | 2022-06-02 | — | — | US | disclosed |
| EP-3988113-A1 | LONG-ACTING COAGULATION FACTORS AND METHODS OF PRODUCING SAME | OPKO Biologics Ltd. (IL) | 2022-04-27 | — | — | EP | disclosed |
| US-20220000990-A1 | LONG-ACTING COAGULATION FACTORS AND METHODS OF PRODUCING SAME | OPKO BIOLOGICS LTD. (IL) | 2022-01-06 | — | — | US | disclosed |
| US-20210371487-A1 | METHODS OF PRODUCING LONG ACTING CTP-MODIFIED POLYPEPTIDES | OPKO BIOLOGICS LTD. (IL) | 2021-12-02 | — | — | US | disclosed |
| CN-113289009-A | Long-acting coagulation factor and production method thereof | OPKO生物科学有限公司 | 2021-08-24 | — | — | CN | disclosed |
| EP-3310347-B1 | LONG-ACTING COAGULATION FACTORS AND METHODS OF PRODUCING SAME | OPKO BIOLOGICS LTD (IL) | 2021-08-04 | — | — | EP | disclosed |
| US-11066658-B2 | Long-acting coagulation factors and methods of producing same | OPKO BIOLOGICS LTD. (IL) | 2021-07-20 | — | — | US | disclosed |
| CN-108289851-B | Long-acting coagulation factor and production method thereof | OPKO生物科学有限公司 | 2021-06-01 | — | — | CN | disclosed |
| US-10960058-B2 | Long-acting coagulation factors and methods of producing same | OPKO BIOLOGICS LTD. (IL) | 2021-03-30 | — | — | US | disclosed |
| WO-1996040743-A2 | INHIBITORS OF FACTOR Xa | COR THERAPEUTICS, INC. (US) | 1996-12-19 | — | — | WO | disclosed |
| WO-1996040744-A1 | KETOHETEROCYCLIC INHIBITORS OF FACTOR Xa | COR THERAPEUTICS, INC. (US) | 1996-12-19 | — | — | WO | disclosed |
| US-5583107-A | ACYLATED BLOOD FACTOR XA AS TREATMENT FOR HEMOPHILIA | COR THERAPEUTICS, INC. (US) | 1996-12-10 | — | — | US | disclosed |
| WO-1996013274-A1 | PROCESS FOR PRODUCTION OF INHIBITED FORMS OF ACTIVATED BLOOD FACTORS | COR THERAPEUTICS, INC. (US) | 1996-05-09 | — | — | WO | disclosed |
| WO-1996000577-A1 | AGENTS AFFECTING THROMBOSIS HEMOSTASIS | COR THERAPEUTICS, INC. (US) | 1996-01-11 | — | — | WO | disclosed |
| EP-0547180-A4 | RECOMBINANT AGENTS AFFECTING THROMBOSIS | COR THERAPEUTICS INC (US) | 1994-11-23 | — | — | EP | disclosed |
| US-5278144-A | Antithrombosis agents | COR THERAPEUTICS, INC. (US) | 1994-01-11 | — | — | US | disclosed |
| EP-0547180-A1 | RECOMBINANT AGENTS AFFECTING THROMBOSIS | COR THERAPEUTICS, INC. (US) | 1993-06-23 | — | — | EP | disclosed |
| WO-1992004378-A1 | RECOMBINANT AGENTS AFFECTING THROMBOSIS | COR THERAPEUTICS, INC. (US) | 1992-03-19 | — | — | WO | disclosed |
| WO-1991009953-A1 | METHODS FOR PRODUCING HYBRID PHOSPHOLIPID-BINDING PROTEINS | ZYMOGENETICS, INC. (US) | 1991-07-11 | — | — | WO | disclosed |