Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 19/20 | 0.95 |
| ▸ | CHRM1 | P11229 | 17/20 | 0.95 |
| ▸ | CHRM4 | P08173 | 13/20 | 0.73 |
| ▸ | CHRM3 | P20309 | 12/20 | 0.73 |
| ▸ | CHRM5 | P08912 | 8/20 | 0.70 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.59 |
| ▸ | DRD1 | P21728 | 1/20 | 0.59 |
| ▸ | DRD5 | P21918 | 1/20 | 0.59 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8879649 | 0.89 | CHRM2 (0.76) | CHRM2CHRM1CHRM4CHRM3CHRM5 | |
| SCHEMBL8881818 | 0.87 | CHRM2 (0.80) | CHRM2CHRM1CHRM4CHRM3CHRM5 | |
| SCHEMBL8880358 | 0.87 | CHRM2 (0.72) | CHRM2CHRM1CHRM4CHRM3CHRM5 | |
| SCHEMBL12648694 | 0.85 | CHRM2 (1.00) | CHRM2CHRM1CHRM4CHRM3CHRM5 | |
| SCHEMBL8881728 | 0.83 | CHRM2 (0.67) | CHRM2CHRM1CHRM4CHRM3CHRM5 | |
| SCHEMBL8880840 | 0.80 | CHRM2 (0.71) | CHRM2CHRM1CHRM4CHRM3CHRM5 | |
| SCHEMBL8879830 | 0.80 | CHRM2 (1.00) | CHRM2CHRM1CHRM4CHRM3CHRM5 | |
| SCHEMBL8879869 | 0.80 | CHRM2 (0.63) | CHRM2CHRM1CHRM4CHRM3CHRM5 | |
| SCHEMBL8879833 | 0.79 | CHRM2 (0.71) | CHRM2CHRM1CHRM4CHRM3CHRM5 | |
| SCHEMBL8880774 | 0.79 | CHRM2 (0.63) | CHRM2CHRM1CHRM4CHRM3CHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5641772-A | Condensed diazepinones, processes for preparing them and agents containing these compounds for treating diseases of the central nervous system and for promoting cerebral blood circulation | DR. KARL THOMAE GMBH (DE) | 1997-06-24 | — | — | US | disclosed |