SCHEMBL8910906

SCHEMBL8910906

CCCCCCCCN(CCCCCCCC)S(=O)(=O)c1ccc(F)c(F)c1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
VCAM1 P19320 2/20 0.54
SERPINE1 P05121 2/20 0.54
SMN1; SMN2 Q16637 2/20 0.51
POLB P06746 1/20 0.51
CNR2 P34972 6/20 0.50
HTT P42858 1/20 0.47
KDM4E B2RXH2 1/20 0.45
CA12 O43570 1/20 0.44
CA2 P00918 1/20 0.44
RAB9A P51151 1/20 0.44
CA9 Q16790 1/20 0.44
SLC22A6 Q4U2R8 1/20 0.44
SLC22A8 Q8TCC7 1/20 0.44
ABCC2 Q92887 1/20 0.44
SLC22A12 Q96S37 1/20 0.44
UGT1A7 Q9HAW7 1/20 0.44
SLC22A11 Q9NSA0 1/20 0.44
P4HB P07237 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.43
MCHR1 Q99705 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27345155 0.80 HTT (0.67) VCAM1SERPINE1SMN1; SMN2HTTKDM4E
SCHEMBL30811628 0.80 HTT (0.67) VCAM1SERPINE1SMN1; SMN2HTTKDM4E
SCHEMBL15682768 0.80 SERPINE1 (0.81) VCAM1SERPINE1SMN1; SMN2POLBCNR2
SCHEMBL15682849 0.80 SERPINE1 (0.81) VCAM1SERPINE1SMN1; SMN2POLBCNR2
SCHEMBL15682789 0.80 SERPINE1 (0.81) VCAM1SERPINE1SMN1; SMN2POLBCNR2
SCHEMBL8911648 0.80 CNR2 (0.67) VCAM1SERPINE1SMN1; SMN2POLBCNR2
SCHEMBL15682659 0.79 SERPINE1 (0.78) VCAM1SERPINE1SMN1; SMN2POLBCNR2
SCHEMBL15682656 0.79 SERPINE1 (0.78) VCAM1SERPINE1SMN1; SMN2POLBCNR2
SCHEMBL15682702 0.79 SERPINE1 (0.78) VCAM1SERPINE1SMN1; SMN2POLBCNR2
SCHEMBL15682701 0.79 SERPINE1 (0.78) VCAM1SERPINE1SMN1; SMN2POLBCNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5591503-A Magnetic recording medium having a thin film magnetic layer and a sulfonamide lubricant THE DOW CHEMICAL COMPANY (US) 1997-01-07 US claimed
WO-1995032500-A1 SULFONAMIDES USEFUL AS LUBRICANTS IN MAGNETIC RECORDING MEDIA THE DOW CHEMICAL COMPANY (US) 1995-11-30 WO claimed
US-5591503-A Magnetic recording medium having a thin film magnetic layer and a sulfonamide lubricant THE DOW CHEMICAL COMPANY (US) 1997-01-07 US disclosed
WO-1995032500-A1 SULFONAMIDES USEFUL AS LUBRICANTS IN MAGNETIC RECORDING MEDIA THE DOW CHEMICAL COMPANY (US) 1995-11-30 WO disclosed