Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 4/20 | 0.42 |
| ▸ | GRIA2 | P42262 | 4/20 | 0.42 |
| ▸ | GRIA3 | P42263 | 4/20 | 0.42 |
| ▸ | GRIA4 | P48058 | 4/20 | 0.42 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.37 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.37 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.37 |
| ▸ | GRIK4 | Q16099 | 1/20 | 0.37 |
| ▸ | GRIK5 | Q16478 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8912076 | 0.85 | GRIA1 (0.39) | GRIA1GRIA2GRIA3GRIA4GRIK1 | |
| SCHEMBL8911174 | 0.82 | GRIA1 (0.36) | GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL8912056 | 0.82 | GRIA1 (0.48) | GRIA1GRIA2GRIA3GRIA4 | |
| Hydrochloric Acid SCHEMBL8912261 | 0.82 | GRIA1 (0.36) | GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL8911163 | 0.80 | GRIA1 (0.36) | GRIA1GRIA2GRIA3GRIA4GRIK1 | |
| SCHEMBL8911793 | 0.80 | GRIA1 (0.38) | GRIA1GRIA2GRIA3GRIA4GRIK1 | |
| SCHEMBL8911955 | 0.79 | GRIA1 (0.36) | GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL8911334 | 0.78 | PDE3B (0.40) | GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL8912360 | 0.78 | GRIA1 (0.46) | GRIA1GRIA2GRIA3GRIA4GRIK1 | |
| SCHEMBL8911544 | 0.78 | GRIA1 (0.36) | GRIA1GRIA2GRIA3GRIA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0698024-B1 | [1,2,4]TRIAZOLO [4,3-a]QUINOXALINE COMPOUNDS, THEIR PREPARATION AND USE | NOVO NORDISK AS (DK) | 1997-01-22 | — | — | EP | claimed |
| EP-0698024-B1 | [1,2,4]TRIAZOLO [4,3-a]QUINOXALINE COMPOUNDS, THEIR PREPARATION AND USE | NOVO NORDISK AS (DK) | 1997-01-22 | — | — | EP | disclosed |
| US-5532236-A | TREATMENT OF PARKINSON'S DISEASE | NOVO NORDISK A/S (DK) | 1996-07-02 | — | — | US | disclosed |