Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 1/20 | 0.65 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.65 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.65 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.65 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.65 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.65 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.65 |
| ▸ | GRIK4 | Q16099 | 1/20 | 0.65 |
| ▸ | GRIK5 | Q16478 | 1/20 | 0.65 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.58 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8911406 | 0.96 | GRIK1 (0.65) | GRIK1GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL8911658 | 0.83 | CA12 (0.50) | GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL8139096 | 0.82 | GRIK1 (0.60) | GRIK1GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL4564672 | 0.81 | GRIA1 (0.67) | GRIK1GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL8911197 | 0.81 | CA12 (0.47) | GRIK1GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL8911151 | 0.81 | GRIK1 (0.43) | GRIK1GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL8911413 | 0.80 | PDE2A (0.43) | GRIK1GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL8912056 | 0.80 | GRIA1 (0.48) | GRIA1GRIA2GRIA3GRIA4 | |
| Ym-90K SCHEMBL2049549 | 0.79 | GRIA1 (1.00) | GRIK1GRIA1GRIA2GRIA3GRIA4 | |
| Ym-90K SCHEMBL29798088 | 0.79 | GRIA1 (1.00) | GRIK1GRIA1GRIA2GRIA3GRIA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0698024-B1 | [1,2,4]TRIAZOLO [4,3-a]QUINOXALINE COMPOUNDS, THEIR PREPARATION AND USE | NOVO NORDISK AS (DK) | 1997-01-22 | — | — | EP | claimed |
| EP-0698024-A1 | 1,2,4]TRIAZOLO 4,3-a]QUINOXALINE COMPOUNDS, THEIR PREPARATION AND USE | NOVO NORDISK AS (DK) | 1996-02-28 | — | — | EP | claimed |
| WO-1994026746-A1 | [1,2,4]TRIAZOLO[4,3-a]QUINOXALINE COMPOUNDS, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1994-11-24 | — | — | WO | claimed |
| EP-0698024-B1 | [1,2,4]TRIAZOLO [4,3-a]QUINOXALINE COMPOUNDS, THEIR PREPARATION AND USE | NOVO NORDISK AS (DK) | 1997-01-22 | — | — | EP | disclosed |
| US-5532236-A | TREATMENT OF PARKINSON'S DISEASE | NOVO NORDISK A/S (DK) | 1996-07-02 | — | — | US | disclosed |
| EP-0698024-A1 | 1,2,4]TRIAZOLO 4,3-a]QUINOXALINE COMPOUNDS, THEIR PREPARATION AND USE | NOVO NORDISK AS (DK) | 1996-02-28 | — | — | EP | disclosed |
| WO-1994026746-A1 | [1,2,4]TRIAZOLO[4,3-a]QUINOXALINE COMPOUNDS, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1994-11-24 | — | — | WO | disclosed |