Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | TOP2A | P11388 | 1/20 | 0.38 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8911899 | 1.00 | ATM (0.52) | ATMNPSR1TOP2ATOP2B | |
| SCHEMBL8912014 | 0.92 | ATM (0.51) | ATMNPSR1 | |
| SCHEMBL8912021 | 0.92 | ATM (0.51) | ATMNPSR1 | |
| SCHEMBL8913775 | 0.92 | ATM (0.50) | ATM | |
| SCHEMBL8913766 | 0.92 | ATM (0.50) | ATM | |
| SCHEMBL8911363 | 0.90 | ATM (0.53) | ATMNPSR1 | |
| SCHEMBL8912043 | 0.90 | ATM (0.53) | ATMNPSR1 | |
| SCHEMBL8911359 | 0.90 | ATM (0.53) | ATMNPSR1 | |
| SCHEMBL8912049 | 0.90 | ATM (0.53) | ATMNPSR1 | |
| SCHEMBL8911408 | 0.89 | ATM (0.47) | ATMNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0799230-A1 | THIENOXAZINONE DERIVATIVES USEFUL AS ANTIVIRAL AGENTS | SMITHKLINE BEECHAM PLC (GB) | 1997-10-08 | — | — | EP | disclosed |
| WO-1996019482-A1 | THIENOXAZINONE DERIVATIVES USEFUL AS ANTIVIRAL AGENTS | SMITHKLINE BEECHAM PLC (GB) | 1996-06-27 | — | — | WO | disclosed |