Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.37 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.37 |
| ▸ | DRD1 | P21728 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8907542 | 0.87 | HRH3 (0.45) | HRH3KDM4EALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL8906886 | 0.87 | HRH3 (0.45) | HRH3KDM4EALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL8912787 | 0.79 | HRH3 (0.60) | HRH3KDM4ELMNASMN1; SMN2MAPT | |
| SCHEMBL10650134 | 0.73 | TSHR (0.52) | ALDH1A1LMNASMN1; SMN2MAPTHTT | |
| SCHEMBL10653978 | 0.73 | TSHR (0.52) | ALDH1A1LMNASMN1; SMN2MAPTHTT | |
| SCHEMBL30307401 | 0.72 | HRH3 (0.53) | HRH3KDM4EALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL10649397 | 0.71 | TSHR (0.53) | ALDH1A1LMNASMN1; SMN2MAPTHTT | |
| SCHEMBL7504362 | 0.70 | HRH3 (0.57) | HRH3LMNAHTTKMT2AADRA1A | |
| SCHEMBL5073627 | 0.68 | HRH3 (0.44) | HRH3ALDH1A1LMNASMN1; SMN2MAPT | |
| SCHEMBL14359324 | 0.68 | HRH3 (0.60) | HRH3KDM4EALDH1A1MAPTADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997048705-A1 | POTASSIUM CHANNEL BLOCKERS | UNIVERSITY COLLEGE LONDON (GB) | 1997-12-24 | — | — | WO | disclosed |