Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.80 |
| ▸ | MEN1 | O00255 | 5/20 | 0.80 |
| ▸ | ATM | Q13315 | 1/20 | 0.80 |
| ▸ | MAPT | P10636 | 2/20 | 0.61 |
| ▸ | GAA | P10253 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8914413 | 0.83 | KMT2A (0.61) | KMT2AMEN1ATMMAPTGAA | |
| SCHEMBL11052922 | 0.77 | KMT2A (0.63) | KMT2AMEN1ATMMAPTGAA | |
| SCHEMBL9694491 | 0.76 | MEN1 (1.00) | KMT2AMEN1ATMMAPTGAA | |
| SCHEMBL9671233 | 0.76 | MEN1 (0.69) | KMT2AMEN1ATMMAPTGAA | |
| SCHEMBL17650674 | 0.75 | GAA (0.64) | KMT2AMEN1ATMMAPTGAA | |
| SCHEMBL13545621 | 0.75 | GAA (0.69) | KMT2AMEN1ATMMAPTGAA | |
| SCHEMBL9671952 | 0.75 | MEN1 (0.73) | KMT2AMEN1ATMMAPTGAA | |
| SCHEMBL11065732 | 0.74 | KMT2A (0.55) | KMT2AMEN1ATMMAPTGAA | |
| SCHEMBL6524461 | 0.74 | KMT2A (0.74) | KMT2AMEN1ATMMAPTGAA | |
| SCHEMBL29367470 | 0.74 | KMT2A (0.74) | KMT2AMEN1ATMMAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5604256-A | (7-(5-(1,3-DIOXANE-5YL)METHOXYIMINO-2-METHYL-8-(2-METHYLBUTYR -OXY)3-OXO-1,2,3,5,6,7,8,8A-OCTAHYDRO-1-NAPHTHYL)-3-HYDROXY-5 -OXOHEPTANOIC ACID AND SALTS | SANKYO COMPANY, LIMITED (JP) | 1997-02-18 | — | — | US | disclosed |
| EP-0570245-B1 | Octahydronaphthalene oxime derivatives for cholesterol biosynthesis inhibition, their preparation and use | SANKYO CO (JP) | 1996-10-30 | — | — | EP | disclosed |
| EP-0570245-A2 | Octahydronaphthalene oxime derivatives for cholesterol biosynthesis inhibition, their preparation and use | SANKYO COMPANY LIMITED (JP) | 1993-11-18 | — | — | EP | disclosed |