Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.47 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.47 |
| ▸ | CCKBR | P32239 | 3/20 | 0.46 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.46 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.46 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.46 |
| ▸ | GRM8 | O00222 | 1/20 | 0.46 |
| ▸ | GRM6 | O15303 | 1/20 | 0.46 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.46 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.46 |
| ▸ | GSR | P00390 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.46 |
| ▸ | GRM5 | P41594 | 1/20 | 0.46 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.46 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.46 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.46 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.46 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.46 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16240308 | 1.00 | DPP4 (0.47) | DPP4DPP9CCKBRS1PR2S1PR1 | |
| SCHEMBL16240309 | 1.00 | DPP4 (0.47) | DPP4DPP9CCKBRS1PR2S1PR1 | |
| SCHEMBL2784601 | 0.98 | S1PR2 (0.48) | DPP4DPP9CCKBRS1PR2S1PR1 | |
| SCHEMBL7565560 | 0.98 | S1PR2 (0.48) | DPP4DPP9CCKBRS1PR2S1PR1 | |
| SCHEMBL6535151 | 0.98 | S1PR2 (0.48) | DPP4DPP9CCKBRS1PR2S1PR1 | |
| SCHEMBL7565565 | 0.98 | S1PR2 (0.48) | DPP4DPP9CCKBRS1PR2S1PR1 | |
| SCHEMBL7572689 | 0.98 | S1PR2 (0.48) | DPP4DPP9CCKBRS1PR2S1PR1 | |
| SCHEMBL7565141 | 0.98 | S1PR2 (0.48) | DPP4DPP9CCKBRS1PR2S1PR1 | |
| SCHEMBL6659268 | 0.98 | S1PR2 (0.48) | DPP4DPP9CCKBRS1PR2S1PR1 | |
| SCHEMBL7571298 | 0.98 | S1PR2 (0.48) | DPP4DPP9CCKBRS1PR2S1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5602179-A | ANTISPASMODIC AGENTS | ROTTA RESEARCH LABORATORIUM S.P.A. (IT) | 1997-02-11 | — | — | US | disclosed |
| EP-0550899-B1 | Process for preparing derivatives of (R) 5-pentylamino-5-oxopentanoic acid with anticholecystokinin activity | ROTTA RESEARCH LAB (IT) | 1995-12-06 | — | — | EP | disclosed |
| US-5391574-A | Antispasmodic agents | ROTTA RESEARCH LABORATORIUM S.P.A. (IT) | 1995-02-21 | — | — | US | disclosed |
| EP-0344184-B1 | DERIVATIVES OF (R) 5-PENTYLAMINO-5-OXOPENTANOIC ACID WITH ANTICHOLECYSTOKININ ACTIVITY | ROTTA RESEARCH LAB (IT) | 1993-11-24 | — | — | EP | disclosed |
| EP-0550899-A1 | Process for preparing derivatives of (R) 5-pentylamino-5-oxopentanoic acid with anticholecystokinin activity | ROTTA RESEARCH LABORATORIUM S.P.A. (IT) | 1993-07-14 | — | — | EP | disclosed |
| US-5130474-A | For treatment of gastrointestinal disorders such as colitis, pancreatitis, antispastic agents and biliary diskinesia | ROTTA RESEARCH LABORATORIUM SPA (IT) | 1992-07-14 | — | — | US | disclosed |
| EP-0344184-A1 | DERIVATIVES OF (R) 5-PENTYLAMINO-5-OXOPENTANOIC ACID WITH ANTICHOLECYSTOKININ ACTIVITY. | ROTTA RESEARCH LAB (IT) | 1989-12-06 | — | — | EP | disclosed |
| WO-1988005774-A1 | DERIVATIVES OF (R) 5-PENTYLAMINO-5-OXOPENTANOIC ACID WITH ANTICHOLECYSTOKININ ACTIVITY | ROTTA RESEARCH LABORATORIUM S.P.A. (IT) | 1988-08-11 | — | — | WO | disclosed |