⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6375136 | 0.73 | — | — | |
| SCHEMBL9333820 | 0.72 | OR51E2 (0.59) | — | |
| SCHEMBL14564211 | 0.72 | OR51E2 (0.59) | — | |
| SCHEMBL9307587 | 0.72 | OR51E2 (0.59) | — | |
| SCHEMBL4331467 | 0.71 | OR51E2 (0.50) | — | |
| SCHEMBL2512864 | 0.71 | CA4 (0.52) | — | |
| SCHEMBL7502708 | 0.71 | — | — | |
| SCHEMBL27777669 | 0.71 | — | — | |
| SCHEMBL30848875 | 0.71 | — | — | |
| SCHEMBL1765577 | 0.69 | OR51E2 (1.00) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5672757-A | ANTITUMOR AGENTS | OHGEN RESEARCH LABORATORIES, LTD. (JP) | 1997-09-30 | — | — | US | disclosed |
| US-5523320-A | FOR TREATMENT OF LEUKEMIA | OHGEN RESEARCH LABORATORIES, LTD. (JP) | 1996-06-04 | — | — | US | disclosed |
| EP-0493064-B1 | Deacetylcolchicine derivatives | OHGEN RESEARCH LAB LTD (JP) | 1995-02-15 | — | — | EP | disclosed |
| EP-0607647-A1 | N-Methyldeacetylcolchiceinamide derivatives | OHGEN RESEARCH LABORATORIES LTD., (JP) | 1994-07-27 | — | — | EP | disclosed |
| US-5220002-A | Antitumor agents | OHGEN RESEARCH LABORATORIES, LTD. (JP) | 1993-06-15 | — | — | US | disclosed |
| EP-0493064-A1 | Deacetylcolchicine derivatives | OHGEN RESEARCH LABORATORIES LTD., (JP) | 1992-07-01 | — | — | EP | disclosed |