SCHEMBL8914360

SCHEMBL8914360

Cc1ccccc1C(=O)C(Cl)(Cl)Cl

nearest known ligand 0.56

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
HPGD P15428 3/20 0.46
ERCC5 P28715 1/20 0.44
FEN1 P39748 1/20 0.44
HTT P42858 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.42
MYC P01106 1/20 0.41
DHODH Q02127 1/20 0.41
ELANE P08246 1/20 0.41
ENPP3 O14638 1/20 0.41
ALPL P05186 1/20 0.41
XIAP P98170 1/20 0.41
THRB P10828 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
KDM4E B2RXH2 1/20 0.41
ALDH1A1 P00352 1/20 0.41
HSD17B10 Q99714 1/20 0.41
POLB P06746 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3869539 0.85 HPGD (0.44) HPGDERCC5FEN1HTTSMN1; SMN2
SCHEMBL1278501 0.83 HPGD (0.43) HPGDERCC5FEN1HTTSMN1; SMN2
SCHEMBL25263550 0.80 CD44 (0.42) HPGDHTTSMN1; SMN2MYCKDM4E
SCHEMBL11847560 0.80 HPGD (0.41) HPGDERCC5FEN1HTTSMN1; SMN2
SCHEMBL7949878 0.80 HPGD (0.47) HPGDERCC5FEN1HTTSMN1; SMN2
SCHEMBL5096830 0.78 HPGD (0.46) HPGDERCC5FEN1HTTSMN1; SMN2
SCHEMBL29645048 0.78 CES1 (0.50) HPGDERCC5FEN1HTTSMN1; SMN2
SCHEMBL19278858 0.78 HPGD (0.46) HPGDERCC5FEN1HTTSMN1; SMN2
SCHEMBL1199962 0.78 CES1 (0.50) HPGDERCC5FEN1HTTSMN1; SMN2
SCHEMBL10455866 0.78 HPGD (0.46) HPGDERCC5FEN1HTTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5607817-A DIALKYLAMINOPHENYL-SUBSTITUTED TRIAZINE SENSITIZER MITSUBISHI CHEMICAL CORPORATION (JP) 1997-03-04 US claimed
US-5607817-A DIALKYLAMINOPHENYL-SUBSTITUTED TRIAZINE SENSITIZER MITSUBISHI CHEMICAL CORPORATION (JP) 1997-03-04 US disclosed
EP-0537630-B1 Photopolymerizable composition MITSUBISHI CHEM CORP (JP) 1996-02-28 EP disclosed
EP-0300410-B1 Photopolymerizable composition MITSUBISHI CHEM IND (JP) 1994-10-26 EP disclosed
EP-0537630-A1 Photopolymerizable composition Mitsubishi Chemical Corporation (JP) 1993-04-21 EP disclosed
US-4966830-A Photopolymerizable composition MITSUBISHI KASEI CORPORATION (JP) 1990-10-30 US disclosed
EP-0300410-A2 Photopolymerizable composition Mitsubishi Chemical Corporation (JP) 1989-01-25 EP disclosed