Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 4/20 | 0.36 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.36 |
| ▸ | PTPN6 | P29350 | 2/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.35 |
| ▸ | HMGB1 | P09429 | 2/20 | 0.35 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.34 |
| ▸ | LTB4R | Q15722 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5885039 | 0.87 | AKR1C2 (0.36) | PTPN1PTPN2PTPN6HMGB1ALDH1A1 | |
| SCHEMBL5885382 | 0.87 | AKR1C2 (0.36) | PTPN1PTPN2PTPN6HMGB1ALDH1A1 | |
| SCHEMBL5885464 | 0.83 | KAT8 (0.33) | MCL1HMGB1ALDH1A1BCL2L1 | |
| SCHEMBL5885053 | 0.82 | CYP3A4 (0.34) | MCL1HMGB1ALDH1A1CYP3A4BCL2L1 | |
| SCHEMBL9502083 | 0.81 | AKR1C2 (0.38) | PTPN1PTPN2PTPN6MCL1HMGB1 | |
| SCHEMBL5885270 | 0.81 | PTPN1 (0.59) | PTPN1PTPN2PTPN6MCL1BCL2L1 | |
| SCHEMBL8915510 | 0.81 | KAT8 (0.39) | PTPN1PTPN2PTPN6MCL1ALDH1A1 | |
| SCHEMBL9652251 | 0.80 | PTPN1 (0.45) | PTPN1PTPN2PTPN6MCL1HMGB1 | |
| SCHEMBL5885048 | 0.80 | CNR1 (0.39) | — | |
| SCHEMBL5884807 | 0.79 | PTPN1 (0.38) | PTPN1PTPN2PTPN6HMGB1CXCL12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5610298-A | Water-soluble anthraquinone compounds, preparation thereof and use thereof as dyes | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-03-11 | — | — | US | disclosed |