SCHEMBL891518

SCHEMBL891518

C=CCCCCCCC[Zn]

nearest known ligand 0.52

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.52
ABCC4 O15439 1/20 0.44
MAPT P10636 1/20 0.44
ALDH1A1 P00352 4/20 0.43
TRPA1 O75762 3/20 0.41
TDP1 Q9NUW8 2/20 0.39
USP2 O75604 1/20 0.39
HPGD P15428 1/20 0.39
LPAR3 Q9UBY5 2/20 0.38
LMNA P02545 2/20 0.38
LPAR2 Q9HBW0 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27745403 1.00
SCHEMBL27724650 0.97
Bromide SCHEMBL19637972 0.94
SCHEMBL891421 0.87
Hydrochloric Acid SCHEMBL8415913 0.84
Bromide SCHEMBL829457 0.84
SCHEMBL10772647 0.83 TSHR (0.69) TSHRABCC4MAPTALDH1A1TRPA1
SCHEMBL18187333 0.83 TSHR (0.69) TSHRABCC4MAPTALDH1A1TRPA1
SCHEMBL18187342 0.83 TSHR (0.69) TSHRABCC4MAPTALDH1A1TRPA1
SCHEMBL18187344 0.83 TSHR (0.69) TSHRABCC4MAPTALDH1A1TRPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120083575-A1 COMB ARCHITECTURE OLEFIN BLOCK COPOLYMERS DOW GLOBAL TECHNOLOGIES LLC (US) 2012-04-05 US claimed
EP-2436703-B1 Comb architecture olefin block copolymers DOW GLOBAL TECHNOLOGIES LLC (US) 2018-04-25 EP disclosed
US-8907034-B2 Comb architecture olefin block copolymers DOW GLOBAL TECHNOLOGIES LLC (US) 2014-12-09 US disclosed
EP-1940896-B1 CATALYTIC OLEFIN BLOCK COPOLYMERS VIA POLYMERIZABLE SHUTTLING AGENT DOW GLOBAL TECHNOLOGIES LLC (US) 2014-10-22 EP disclosed
US-8415434-B2 Catalytic olefin block copolymers via polymerizable shuttling agent DOW GLOBAL TECHNOLOGIES LLC (US) 2013-04-09 US disclosed
US-20120083575-A1 COMB ARCHITECTURE OLEFIN BLOCK COPOLYMERS DOW GLOBAL TECHNOLOGIES LLC (US) 2012-04-05 US disclosed
US-20110092651-A1 Catalytic Olefin Block Copolymers Via Polymerizable Shuttling Agent ARRIOLA DANIEL J 2011-04-21 US disclosed
US-7858707-B2 Catalytic olefin block copolymers via polymerizable shuttling agent DOW GLOBAL TECHNOLOGIES INC. (US) 2010-12-28 US disclosed
US-20090163667-A1 CATALYTIC OLEFIN BLOCK COPOLYMERS VIA POLYMERIZABLE SHUTTLING AGENT DOW GLOBAL TECHNOLOGIES INC. (US) 2009-06-25 US disclosed
EP-1940896-A1 CATALYTIC OLEFIN BLOCK COPOLYMERS VIA POLYMERIZABLE SHUTTLING AGENT Dow Global Technologies Inc. (US) 2008-07-09 EP disclosed
WO-2007035492-A1 CATALYTIC OLEFIN BLOCK COPOLYMERS VIA POLYMERIZABLE SHUTTLING AGENT DOW GLOBAL TECHNOLOGIES INC. (US) 2007-03-29 WO disclosed