Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.42 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.42 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.42 |
| ▸ | FABP2 | P12104 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.42 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.42 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20773094 | 0.85 | CDK1 (0.44) | FOLH1KMT2AMEN1PTGS1PTGS2 | |
| SCHEMBL3717925 | 0.83 | AKR1C3 (0.53) | FOLH1AKR1C2AKR1C3 | |
| SCHEMBL28895383 | 0.81 | FOLH1 (0.47) | FOLH1KMT2AAKR1C3LMNACYP1A2 | |
| SCHEMBL9954274 | 0.81 | MEN1 (0.43) | FOLH1KMT2AMEN1PTGS1PTGS2 | |
| SCHEMBL8913632 | 0.81 | HTT (0.51) | KMT2AMEN1PTGS1PTGS2TSHR | |
| SCHEMBL23521242 | 0.81 | FOLH1 (0.53) | FOLH1KMT2AMEN1AKR1C2AKR1C1 | |
| SCHEMBL3431160 | 0.80 | FOLH1 (0.47) | FOLH1KMT2AMEN1PTGS1PTGS2 | |
| SCHEMBL1927711 | 0.78 | FOLH1 (0.53) | FOLH1KMT2AMEN1LMNAMAPT | |
| SCHEMBL29201438 | 0.78 | KAT6A (0.53) | KMT2AMEN1PTGS1PTGS2AKR1C2 | |
| SCHEMBL28589720 | 0.78 | PTGS1 (0.37) | KMT2AMEN1PTGS1PTGS2AKR1C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109111451-B | Dihydropyrimidine compound and application thereof in medicine | 广东东阳光药业有限公司 | 2020-08-11 | — | — | CN | disclosed |
| CN-110891939-A | Benzazepine derivatives | 大塚制药株式会社 | 2020-03-17 | — | — | CN | disclosed |
| US-5651919-A | Benzyl ether derivative and composition containing the same | CITIZEN WATCH CO., LTD. (JP) | 1997-07-29 | — | — | US | disclosed |