Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 12/20 | 0.58 |
| ▸ | SRD5A1 | P18405 | 6/20 | 0.58 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8634214 | 0.89 | SRD5A2 (0.74) | SRD5A2SRD5A1 | |
| SCHEMBL8631362 | 0.89 | SRD5A2 (0.74) | SRD5A2SRD5A1 | |
| SCHEMBL8630916 | 0.87 | SRD5A2 (0.64) | SRD5A2SRD5A1 | |
| SCHEMBL8634494 | 0.86 | SRD5A2 (0.77) | SRD5A2SRD5A1 | |
| SCHEMBL8913926 | 0.85 | SRD5A2 (0.57) | SRD5A2SRD5A1ESR1ARESR2 | |
| SCHEMBL8633663 | 0.85 | SRD5A2 (0.61) | SRD5A2SRD5A1ESR1ARESR2 | |
| SCHEMBL8633243 | 0.85 | SRD5A2 (0.60) | SRD5A2SRD5A1ESR1ARESR2 | |
| SCHEMBL8634212 | 0.84 | SRD5A2 (0.63) | SRD5A2SRD5A1 | |
| SCHEMBL8633572 | 0.83 | SRD5A2 (0.57) | SRD5A2SRD5A1 | |
| SCHEMBL8634149 | 0.83 | SRD5A2 (0.57) | SRD5A2SRD5A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0567271-B1 | Steroid derivatives for the treatment of prostatic hypertrophy, their preparation and uses | SANKYO CO (JP) | 1997-07-02 | — | — | EP | disclosed |
| EP-0725074-A2 | Compounds suitable for use as intermediates in the preparation of Androst-3,5-dien-3-carboxy derivatives | SANKYO COMPANY LIMITED (JP) | 1996-08-07 | — | — | EP | disclosed |
| US-5536714-A | Steroid derivatives for the treatment of prostatic hypertrophy their preparation and uses | SANKYO COMPANY, LIMITED (JP) | 1996-07-16 | — | — | US | disclosed |
| EP-0567271-A2 | Steroid derivatives for the treatment of prostatic hypertrophy, their preparation and uses | SANKYO COMPANY LIMITED (JP) | 1993-10-27 | — | — | EP | disclosed |