SCHEMBL8915539

SCHEMBL8915539

NC(N)CC(Cc1ccccc1)Cc1ccccc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 2/20 0.58
SLC6A2 P23975 2/20 0.54
TAAR1 Q96RJ0 2/20 0.54
MAOA P21397 1/20 0.54
SLC6A4 P31645 1/20 0.54
SLC6A3 Q01959 1/20 0.54
SIGMAR1 Q99720 1/20 0.54
CYP2A6 P11509 1/20 0.54
ADORA2A P29274 1/20 0.54
ADORA1 P30542 1/20 0.54
ANPEP P15144 2/20 0.50
CYP2D6 P10635 1/20 0.50
ALPI P09923 1/20 0.48
PKM P14618 1/20 0.48
PTGS1 P23219 1/20 0.48
XIAP P98170 1/20 0.48
SLC7A5 Q01650 1/20 0.48
SLC1A3 P43003 2/20 0.46
SLC1A2 P43004 2/20 0.46
SLC1A1 P43005 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL708446 0.79 EPHX1 (0.70) EPHX1SLC6A2TAAR1MAOASLC6A4
SCHEMBL4981467 0.79 EPHX1 (0.60) EPHX1SLC6A2TAAR1MAOASLC6A4
Hydrochloric Acid SCHEMBL15758369 0.77 EPHX1 (0.67) EPHX1SLC6A2TAAR1MAOASLC6A4
SCHEMBL29522649 0.77 SLC7A5 (0.71) ANPEPALPIPKMPTGS1XIAP
Ammonia Solution, Strong SCHEMBL21412646 0.76 EPHX1 (0.57) EPHX1SLC6A2TAAR1MAOASLC6A4
SCHEMBL11145503 0.76 EPHX1 (0.52) EPHX1SLC6A2TAAR1MAOASLC6A4
SCHEMBL6563096 0.75 EPHX1 (0.56) EPHX1SLC6A2TAAR1MAOASLC6A4
SCHEMBL516032 0.75 EPHX1 (0.56) EPHX1SLC6A2TAAR1MAOASLC6A4
SCHEMBL24017042 0.74 EPHX1 (0.70) EPHX1SLC6A2TAAR1MAOASLC6A4
SCHEMBL9536448 0.74 EPHX1 (0.70) EPHX1SLC6A2TAAR1MAOASLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5677350-A Inhibition of cancer cell growth, proliferation, and metastasis using N,N'-dα,ω-diaminoalkanes WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 1997-10-14 US disclosed
WO-1996040096-A1 INHIBITION OF CANCER CELL GROWTH, PROLIFERATION AND METASTASIS USING N,N'-DIBENZYL-α,φ-DIAMINOALKANES WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 1996-12-19 WO disclosed