SCHEMBL8915856

SCHEMBL8915856

CCCC(N)(Cc1ccccc1)Cc1ccccc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 2/20 0.56
TAAR1 Q96RJ0 2/20 0.56
SMN1; SMN2 Q16637 1/20 0.45
HIF1A Q16665 1/20 0.45
TP53 P04637 1/20 0.42
LMNA P02545 1/20 0.42
CYP2D6 P10635 1/20 0.42
CYP1A2 P05177 1/20 0.39
CYP2C9 P11712 1/20 0.39
CYP2C19 P33261 1/20 0.39
TRPA1 O75762 1/20 0.37
LOXL2 Q9Y4K0 1/20 0.37
MAOA P21397 3/20 0.37
MAOB P27338 2/20 0.37
ARG1 P05089 1/20 0.37
ARG2 P78540 1/20 0.37
KDM4E B2RXH2 1/20 0.36
POLB P06746 1/20 0.36
SLC6A4 P31645 1/20 0.35
SLC6A3 Q01959 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL28491186 0.98 SLC6A2 (0.54) SLC6A2TAAR1SMN1; SMN2HIF1ATP53
SCHEMBL25288700 0.96 SLC6A2 (0.56) SLC6A2TAAR1SMN1; SMN2HIF1ATP53
Hydrochloric Acid SCHEMBL17710430 0.94 SLC6A2 (0.54) SLC6A2TAAR1SMN1; SMN2HIF1ATP53
SCHEMBL27893438 0.86 SLC6A2 (0.50) SLC6A2TAAR1SMN1; SMN2HIF1ATP53
Methylamine SCHEMBL27796046 0.86 SLC6A2 (0.50) SLC6A2TAAR1SMN1; SMN2HIF1ATP53
SCHEMBL11094959 0.84 SLC6A2 (0.48) SLC6A2TAAR1SMN1; SMN2TP53
SCHEMBL11097970 0.84 SLC6A2 (0.48) SLC6A2TAAR1SMN1; SMN2TP53
SCHEMBL9180309 0.84 SLC6A2 (0.48) SLC6A2TAAR1SMN1; SMN2TP53
SCHEMBL28713655 0.84 SLC6A2 (0.48) SLC6A2TAAR1SMN1; SMN2TP53
SCHEMBL9329228 0.84 SLC6A2 (0.48) SLC6A2TAAR1SMN1; SMN2TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0383089-B1 Cold curing reactive resin blend and its use BAYER AG (DE) 1994-04-06 EP claimed
US-5084544-A Reaction of polyepoxides and polyisocyanates to form polyurethanes BAYER AKTIENGESELLSCHAFT (DE) 1992-01-28 US claimed
CN-119365447-A Process for preparing substantially nitrosamine-free, peroxide-free, substantially colorless amine oxide 巴斯夫欧洲公司 2025-01-24 CN disclosed
US-5639880-A REACTING AMINES WITH HYDROGEN/OXYGEN MIXTURES IN PRESENCE OF OXIDATION CATALYSTS OF THE ELEMENTS OF GROUP 8 OF PERIODIC TABLE ON TITANIUM SILICATES, VANADIUM SILICATES OR MIXTURES BASF AKTIENGESELLSCHAFT (DE) 1997-06-17 US disclosed
EP-0424965-A1 Amine oxide process ETHYL CORPORATION (US) 1991-05-02 EP disclosed
US-4960934-A Amine oxide process ETHYL CORPORATION (US) 1990-10-02 US disclosed
US-4942260-A REACTION OF A TERT-AMINE WITH HYDROGEN PEROXIDE IN THE PRESENCE OF CATALYTIC CARBON DIOXIDE ETHYL CORPORATION (US) 1990-07-17 US disclosed
EP-0356918-A1 Amine oxide process ETHYL CORPORATION (US) 1990-03-07 EP disclosed
US-4889954-A DIALKYLCARBONATE CATALYST ETHYL CORPORATION (US) 1989-12-26 US disclosed
EP-0307184-A2 Preparation of Amine Oxides ETHYL CORPORATION (US) 1989-03-15 EP disclosed