Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8916543 | 0.79 | EPHX2 (0.45) | HTR2CEPHX2 | |
| SCHEMBL2299768 | 0.77 | EPHX2 (0.51) | HTR2CEPHX2 | |
| SCHEMBL13116668 | 0.76 | HTR2C (0.56) | HTR2CEPHX2 | |
| Water SCHEMBL8709610 | 0.76 | EPHX2 (0.50) | HTR2CEPHX2 | |
| SCHEMBL122262 | 0.73 | USP2 (0.55) | HTR2CEPHX2 | |
| SCHEMBL14385534 | 0.72 | HTR2C (0.40) | HTR2CEPHX2 | |
| SCHEMBL23561114 | 0.72 | HTR2C (0.49) | HTR2CEPHX2 | |
| SCHEMBL13116675 | 0.71 | HTR2C (0.42) | HTR2CEPHX2 | |
| SCHEMBL859700 | 0.71 | HRH4 (0.72) | — | |
| SCHEMBL8916808 | 0.71 | HTR2C (0.38) | HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5686610-A | Pyridyl piperazine compound | PHARMACIA & UPJOHN COMPANY (US) | 1997-11-11 | — | — | US | disclosed |
| US-5599930-A | Substituted indoles as anti-AIDS pharmaceuticals | THE UPJOHN COMPANY (US) | 1997-02-04 | — | — | US | disclosed |
| WO-1993001181-A1 | SUBSTITUTED INDOLES AS ANTI-AIDS PHARMACEUTICALS | THE UPJOHN COMPANY (US) | 1993-01-21 | — | — | WO | disclosed |