Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.31 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8915156 | 1.00 | POLB (0.33) | POLBCTDSP1TDP1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL8916057 | 0.98 | POLB (0.32) | POLBCTDSP1TDP1MEN1KMT2A | |
| SCHEMBL9636123 | 0.80 | POLB (0.31) | POLBCTDSP1TDP1 | |
| SCHEMBL9665014 | 0.80 | POLB (0.31) | POLBCTDSP1TDP1 | |
| Hydrochloric Acid SCHEMBL9431771 | 0.79 | POLB (0.30) | POLBCTDSP1TDP1 | |
| SCHEMBL26605048 | 0.78 | POLB (0.36) | POLBCTDSP1TDP1CYP2D6 | |
| Hydrochloric Acid SCHEMBL8916228 | 0.77 | CYP2D6 (0.42) | POLBCYP2D6 | |
| Hydrochloric Acid SCHEMBL8917378 | 0.77 | CYP2D6 (0.42) | POLBCYP2D6 | |
| Hydrochloric Acid SCHEMBL8918371 | 0.77 | CYP2D6 (0.42) | POLBCYP2D6 | |
| SCHEMBL14986206 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5625059-A | Process for the manufacture of 4-acetoxy-3-hydroxyethyl-azetidinone | CIBA-GEIGY CORPORATION (US) | 1997-04-29 | — | — | US | disclosed |
| US-5312914-A | Process for the manufacture of 4-acetoxy-3-hydroxyethyl-azetidinone | CIBA-GEIGY CORP (US) | 1994-05-17 | — | — | US | disclosed |
| EP-0279781-A2 | Process for the preparation of 4-acetoxy-3-hydroxyethyl-acetidinone | CIBA-GEIGY AG (CH) | 1988-08-24 | — | — | EP | disclosed |