Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 1/20 | 0.56 |
| ▸ | FNTB | P49356 | 1/20 | 0.56 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5400265 | 1.00 | FNTA (0.56) | FNTAFNTBGGPS1 | |
| SCHEMBL8916847 | 1.00 | FNTA (0.56) | FNTAFNTBGGPS1 | |
| SCHEMBL16079902 | 0.98 | FNTA (0.59) | FNTAFNTBGGPS1 | |
| SCHEMBL8916061 | 0.98 | FNTA (0.59) | FNTAFNTBGGPS1 | |
| SCHEMBL2875241 | 0.98 | FNTA (0.59) | FNTAFNTBGGPS1 | |
| SCHEMBL9127288 | 0.93 | FNTA (0.53) | FNTAFNTBGGPS1 | |
| SCHEMBL9128237 | 0.91 | FNTA (0.56) | FNTAFNTBGGPS1 | |
| SCHEMBL2697221 | 0.91 | FNTA (0.56) | FNTAFNTBGGPS1 | |
| SCHEMBL8390164 | 0.86 | FNTA (0.50) | FNTA | |
| SCHEMBL9633689 | 0.84 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0513761-A2 | Bisphosphonate squalene synthetase inhibitors | E.R. SQUIBB & SONS, INC. (US) | 1992-11-19 | — | — | EP | claimed |
| US-5157027-A | Anticholesterol agents | E. R. SQUIBB & SONS, INC. (US) | 1992-10-20 | — | — | US | claimed |
| US-5624917-A | Method of inhibiting squalene synthetase | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-04-29 | — | — | US | disclosed |
| EP-0541037-A2 | Squalene synthetase inhibitory composition and use thereof | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1993-05-12 | — | — | EP | disclosed |
| EP-0513761-A2 | Bisphosphonate squalene synthetase inhibitors | E.R. SQUIBB & SONS, INC. (US) | 1992-11-19 | — | — | EP | disclosed |
| US-5157027-A | Anticholesterol agents | E. R. SQUIBB & SONS, INC. (US) | 1992-10-20 | — | — | US | disclosed |