Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | NPY1R | P25929 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.47 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | TLR2 | O60603 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26310077 | 0.83 | HTT (0.52) | HTTATMKMT2ANPY1RSMN1; SMN2 | |
| SCHEMBL10558453 | 0.81 | HTT (0.62) | HTTATMKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL8918338 | 0.80 | KMT2A (0.52) | HTTATMKMT2ANPY1RSMN1; SMN2 | |
| SCHEMBL8918763 | 0.80 | KMT2A (0.55) | HTTATMKMT2ANPY1RSMN1; SMN2 | |
| SCHEMBL5666551 | 0.78 | HTT (0.53) | HTTATMKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL4986522 | 0.78 | HTT (0.56) | HTTATMKMT2ANPY1RSMN1; SMN2 | |
| SCHEMBL10311684 | 0.77 | HTT (0.64) | HTTATMKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL21794977 | 0.76 | KMT2A (0.56) | HTTATMKMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL10448601 | 0.75 | HTT (0.56) | HTTATMKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL5076600 | 0.75 | KMT2A (0.52) | HTTATMKMT2ASMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5656253-A | Ligands useful in radiographic imaging | MALLINCKRODT MEDICAL, INC. (US) | 1997-08-12 | — | — | US | disclosed |