Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 15/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | BLM | P54132 | 1/20 | 0.57 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.57 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | AKT2 | P31751 | 1/20 | 0.39 |
| ▸ | CLK2 | P49760 | 1/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.39 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5631019 | 0.84 | HSP90AA1 (0.60) | HSP90AA1MEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL29948904 | 0.82 | HSP90AA1 (0.83) | HSP90AA1MEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL3102522 | 0.82 | HSP90AA1 (0.83) | HSP90AA1MEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL29748943 | 0.82 | HSP90AA1 (0.83) | HSP90AA1MEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL8917622 | 0.81 | HSP90AA1 (0.65) | HSP90AA1MEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL9116312 | 0.81 | HSP90AA1 (0.57) | HSP90AA1MEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL5632986 | 0.80 | HSP90AA1 (0.83) | HSP90AA1MEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL9118401 | 0.76 | HSP90AA1 (0.56) | HSP90AA1MEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL9119941 | 0.76 | HSP90AA1 (0.75) | HSP90AA1MEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL8917638 | 0.76 | HSP90AA1 (0.52) | HSP90AA1MEN1KMT2ACYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5621007-A | Method for regulation of transmembrane chloride conductance | BRISTOL-MYERS SQUIBB COMPANY (US) | 1997-04-15 | — | — | US | disclosed |