Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | GCGR | P47871 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.37 |
| ▸ | ERN1 | O75460 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.36 |
| ▸ | ADCY1 | Q08828 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8918235 | 0.78 | ERN1 (0.49) | LMNAMAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL1646479 | 0.78 | MAPT (0.42) | LMNAMAPTKMT2APOLBTDP1 | |
| SCHEMBL11672033 | 0.78 | GRM2 (0.49) | LMNAGCGRMAPK14GAAKMT2A | |
| SCHEMBL4860000 | 0.77 | NPC1 (0.47) | LMNAMAPTKMT2ATDP1MEN1 | |
| SCHEMBL12699499 | 0.75 | GRM2 (0.47) | LMNAGCGRMAPK14GAAKMT2A | |
| SCHEMBL15060599 | 0.75 | GRM2 (0.50) | LMNAGCGRMAPK14MAPTKMT2A | |
| SCHEMBL14840571 | 0.75 | ERN1 (0.45) | GCGRMAPK14GAAALDH1A1ERN1 | |
| SCHEMBL11671157 | 0.74 | GCGR (0.46) | LMNAGCGRMAPK14GAAMAPT | |
| SCHEMBL14306404 | 0.74 | ERN1 (0.44) | LMNAMAPTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL2480683 | 0.73 | ERN1 (0.41) | LMNAMAPTALDH1A1RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5622953-A | DRUG RESISTANT TO ANTICANCER CHEMOTHERAPEUTIC DRUG | BASF AKTIENGESELLSCHAFT (DE) | 1997-04-22 | — | — | US | disclosed |