Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.33 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
| ▸ | NTRK1 | P04629 | 4/20 | 0.31 |
| ▸ | PIM1 | P11309 | 4/20 | 0.31 |
| ▸ | ACVR1 | Q04771 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8918135 | 0.87 | MAP3K7 (0.32) | — | |
| SCHEMBL8918240 | 0.86 | HPGD (0.30) | — | |
| SCHEMBL8922867 | 0.85 | KDM4E (0.34) | — | |
| SCHEMBL8922857 | 0.85 | KDM4E (0.34) | — | |
| SCHEMBL8920430 | 0.84 | MAP3K7 (0.32) | — | |
| SCHEMBL8920805 | 0.84 | PLK4 (0.33) | MKNK2PIM1 | |
| SCHEMBL8918506 | 0.77 | KDM4E (0.32) | — | |
| SCHEMBL8919997 | 0.73 | KDM5C (0.41) | MKNK1MKNK2 | |
| SCHEMBL8919974 | 0.73 | KDM5C (0.41) | MKNK1MKNK2 | |
| SCHEMBL8918530 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5691366-A | UNSATURATED NITRO OXIME FORMED BY REACTION OF DINITROGEN TRIOXIDE WITH DIOLEFIN ETHER, SULFIDE OR AMINE TO BE USED AS VASODILATORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-11-25 | — | — | US | disclosed |