Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.49 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | SLC18A3 | Q16572 | 3/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29450354 | 0.92 | NOTUM (0.55) | NOTUMCNR2SLC18A3SIGMAR1SLC6A2 | |
| SCHEMBL538625 | 0.92 | NOTUM (0.55) | NOTUMCNR2SLC18A3SIGMAR1SLC6A2 | |
| Iodide SCHEMBL28271700 | 0.90 | NOTUM (0.53) | NOTUMCNR2SLC18A3SIGMAR1SLC6A2 | |
| Bromobenzene SCHEMBL27896182 | 0.82 | NOTUM (0.46) | NOTUMCNR2SLC18A3SIGMAR1SLC6A2 | |
| Perchlorate SCHEMBL30037037 | 0.82 | NOTUM (0.50) | NOTUMCNR2SLC18A3SIGMAR1SLC6A2 | |
| SCHEMBL18054866 | 0.78 | NOTUM (0.49) | NOTUMCNR2SLC6A2SLC6A4MAPT | |
| SCHEMBL29715746 | 0.78 | NOTUM (0.41) | NOTUMCNR2SLC18A3SIGMAR1SLC6A2 | |
| SCHEMBL29715681 | 0.78 | NOTUM (0.45) | NOTUMCNR2SLC18A3SIGMAR1SLC6A2 | |
| SCHEMBL9550828 | 0.77 | NOTUM (0.45) | NOTUMCNR2SLC18A3SIGMAR1TSHR | |
| SCHEMBL17771729 | 0.77 | RECQL (0.37) | NOTUMKDM4EMAPTGAARECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0783483-A1 | METHOD FOR PREPARING PHOTOCHROMIC COMPOUNDS OF THE SPIRO INDOLIN- 2,3']-BENZOXAZINE] RINGED TYPE | ESSILOR INTERNATIONAL COMPAGNIE GENERALE D'OPTIQUE (FR) | 1997-07-16 | — | — | EP | disclosed |
| WO-1996003368-A1 | METHOD FOR PREPARING PHOTOCHROMIC COMPOUNDS OF THE SPIRO[INDOLIN-[2,3']-BENZOXAZINE] RINGED TYPE | ESSILOR INTERNATIONAL (COMPAGNIE GENERALE D'OPTIQUE) (FR) | 1996-02-08 | — | — | WO | disclosed |