SCHEMBL8919759

SCHEMBL8919759

CCOc1cccc2c1C1(CCCOO1)NC2=N

nearest known ligand 0.31

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.31
KDM4E B2RXH2 3/20 0.31
MAPT P10636 3/20 0.31
HTR2A P28223 2/20 0.31
HTR2B P41595 2/20 0.31
MEN1 O00255 2/20 0.31
KMT2A Q03164 2/20 0.31
HTR2C P28335 1/20 0.31
POLB P06746 1/20 0.31
RECQL P46063 1/20 0.31
BLM P54132 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
PPARG P37231 1/20 0.31
STAT3 P40763 1/20 0.31
NCOA2 Q15596 1/20 0.31
RXFP1 Q9HBX9 1/20 0.31
DRD2 P14416 1/20 0.31
ADRB2 P07550 1/20 0.30
HTR1A P08908 1/20 0.30
SLC6A2 P23975 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8917905 0.88 PDE5A (0.33) MAPTHTR2BMEN1KMT2ASLC6A3
SCHEMBL8920255 0.88 PDE5A (0.33) MAPTHTR2BMEN1KMT2ASLC6A3
SCHEMBL8922881 0.86 ORAI1 (0.30)
SCHEMBL8919056 0.82 PDK2 (0.34) ALDH1A1KDM4EMAPTHTR2AHTR2B
SCHEMBL8918900 0.80
SCHEMBL8918980 0.79 DDB1 (0.30) DDB1CRBN
SCHEMBL8921082 0.77 PDE7A (0.32)
SCHEMBL8920443 0.77
SCHEMBL8920555 0.75 PDK2 (0.34) ALDH1A1KDM4EMEN1KMT2APOLB
SCHEMBL8920391 0.75 CYP3A4 (0.36) ALDH1A1KDM4EMAPTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5691272-A Carboxylate and heat-sensitive recording material using same MITSUI TOATSU CHEMICALS, INC. (JP) 1997-11-25 US disclosed
US-5559247-A Carboxylate and heat-sensitive recording material using same MITSUI TOATSU CHEMICALS, INC. (JP) 1996-09-24 US disclosed
EP-0679640-A1 Carboxylate and heat-sensitive recording material using same MITSUI TOATSU CHEMICALS, Inc. (JP) 1995-11-02 EP disclosed