Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.46 |
| ▸ | FER | P16591 | 1/20 | 0.46 |
| ▸ | LTK | P29376 | 1/20 | 0.46 |
| ▸ | CDK8 | P49336 | 1/20 | 0.46 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.46 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.46 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.46 |
| ▸ | GSK3B | P49841 | 3/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8919879 | 0.87 | CYP1A2 (0.57) | CYP1A2SMN1; SMN2ALDH1A1ALOX15MAPK10 | |
| SCHEMBL7980321 | 0.79 | MAPT (0.56) | CYP1A2SMN1; SMN2ALDH1A1ALOX15MAPK10 | |
| SCHEMBL1749823 | 0.74 | GAA (0.50) | CYP1A2SMN1; SMN2ALDH1A1MAPTGAA | |
| SCHEMBL15618396 | 0.73 | PTPRC (0.38) | CYP1A2SMN1; SMN2ALDH1A1ALOX15MAPT | |
| SCHEMBL5937366 | 0.73 | CYP1A2 (1.00) | CYP1A2SMN1; SMN2ALDH1A1ALOX15MAPK10 | |
| SCHEMBL2420515 | 0.71 | CYP1A2 (0.77) | CYP1A2SMN1; SMN2ALDH1A1ALOX15MAPK10 | |
| SCHEMBL554552 | 0.71 | MAPT (0.46) | CYP1A2SMN1; SMN2ALDH1A1HSD17B10MAPT | |
| SCHEMBL5178865 | 0.69 | CYP1A2 (0.80) | CYP1A2SMN1; SMN2ALDH1A1ALOX15MAPK10 | |
| SCHEMBL2203198 | 0.68 | LRRK2 (0.50) | CYP1A2SMN1; SMN2ALDH1A1MAPTGAA | |
| SCHEMBL13629273 | 0.68 | CYP1A2 (0.57) | CYP1A2SMN1; SMN2ALDH1A1ALOX15MAPK10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5616620-A | HYPOTENSIVE AGENTS | KARL THOMAE GMBH (DE) | 1997-04-01 | — | — | US | disclosed |