⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3197969 | 0.63 | — | — | |
| SCHEMBL8922295 | 0.55 | — | — | |
| SCHEMBL2049064 | 0.55 | — | — | |
| SCHEMBL23519840 | 0.51 | — | — | |
| SCHEMBL15690190 | 0.51 | — | — | |
| SCHEMBL15690191 | 0.51 | — | — | |
| SCHEMBL20245049 | 0.51 | — | — | |
| SCHEMBL30350024 | 0.45 | — | — | |
| SCHEMBL30205724 | 0.43 | — | — | |
| SCHEMBL18321328 | 0.35 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5674879-A | Compositions including and methods of using conformationally restricted angiotensin II antagonist | G.D. SEARLE & CO. (US) | 1997-10-07 | — | — | US | disclosed |