⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2656115 | 0.76 | — | — | |
| SCHEMBL16704009 | 0.65 | — | — | |
| SCHEMBL1064444 | 0.62 | — | — | |
| SCHEMBL302906 | 0.59 | — | — | |
| SCHEMBL4685779 | 0.59 | — | — | |
| SCHEMBL573400 | 0.59 | — | — | |
| SCHEMBL434948 | 0.55 | — | — | |
| Ethylene Glycol SCHEMBL8013339 | 0.39 | TSHR (1.00) | — | |
| Ethylene Glycol SCHEMBL49878 | 0.39 | — | — | |
| Ethylene Glycol SCHEMBL1332716 | 0.39 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115443275-A | Condensed pyridine derivatives substituted with amide functions as ACSS2 inhibitors | 默克专利股份公司 | 2022-12-06 | — | — | CN | claimed |
| CN-115443275-A | Condensed pyridine derivatives substituted with amide functions as ACSS2 inhibitors | 默克专利股份公司 | 2022-12-06 | — | — | CN | disclosed |
| CN-101511923-A | Polyester polymer and copolymer compositions containing titanium and yellow colorants | EASTMAN CHEM CO (US) | 2009-08-19 | — | — | CN | disclosed |
| US-5616579-A | ADMINISTERING TO MAMMALS TO PREVENT GASTRIC ULCER | SANKYO COMPANY, LIMITED (JP) | 1997-04-01 | — | — | US | disclosed |
| EP-0562833-B1 | Anti-ulcer pyridyloxy derivatives, their preparation and uses | SANKYO CO (JP) | 1996-05-08 | — | — | EP | disclosed |
| CN-1081437-A | Antiulcer pyridine oxygen derivative, their preparation method and purposes | SANKYO CO (JP) | 1994-02-02 | — | — | CN | disclosed |
| EP-0562833-A1 | Anti-ulcer pyridyloxy derivatives, their preparation and uses | SANKYO COMPANY LIMITED (JP) | 1993-09-29 | — | — | EP | disclosed |