Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8925220 | 0.78 | PDE4A (0.32) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL6719860 | 0.76 | PDE4A (0.31) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8014580 | 0.73 | — | — | |
| SCHEMBL29176442 | 0.67 | — | — | |
| SCHEMBL824165 | 0.66 | — | — | |
| SCHEMBL5705514 | 0.66 | CHEK1 (0.32) | — | |
| SCHEMBL29459645 | 0.66 | — | — | |
| SCHEMBL29445564 | 0.66 | — | — | |
| SCHEMBL19743838 | 0.64 | — | — | |
| SCHEMBL8182354 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-9124613-A | — | — | None | — | — | JP | disclosed |
| JP-H09124613-A | 4,5-DIHALOGENO-6-DIHALOGENOMETHYLPYRIMIDINE AND PRODUCTION THEREOF | UBE IND LTD | 1997-05-13 | — | — | JP | disclosed |