⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3600587 | 0.85 | — | — | |
| SCHEMBL3514393 | 0.65 | — | — | |
| Hydrochloric Acid SCHEMBL29771648 | 0.57 | — | — | |
| SCHEMBL188021 | 0.57 | — | — | |
| SCHEMBL22536543 | 0.54 | — | — | |
| SCHEMBL3584063 | 0.53 | — | — | |
| SCHEMBL15132060 | 0.51 | — | — | |
| SCHEMBL29342710 | 0.48 | — | — | |
| SCHEMBL20245049 | 0.45 | — | — | |
| SCHEMBL11667726 | 0.45 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119119189-A | Polypeptides having MMP2 inhibitory effect | 大正制药株式会社 | 2024-12-13 | — | — | CN | disclosed |
| CN-114450294-B | Polypeptides having MMP2 inhibitory effect | 大正制药株式会社 | 2024-11-26 | — | — | CN | disclosed |
| US-20240199692-A1 | POLYPEPTIDE HAVING MMP2-INHIBITORY EFFECT | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2024-06-20 | — | — | US | disclosed |
| WO-2023204170-A1 | PROPHYLACTIC OR THERAPEUTIC AGENT, FOR LUNG INFLAMMATION AND FIBROSIS, CONTAINING COMPOUND HAVING MMP2 INHIBITORY ACTIVITY AS ACTIVE INGREDIENT | 大正製薬株式会社 | 2023-10-26 | — | — | WO | disclosed |
| WO-2022234867-A1 | SULFONAMIDE HAVING MMP 7-INHIBITING ACTION | 大正製薬株式会社 | 2022-11-10 | — | — | WO | disclosed |
| EP-4056581-A1 | POLYPEPTIDE HAVING MMP2-INHIBITORY EFFECT | Taisho Pharmaceutical Co., Ltd. (JP) | 2022-09-14 | — | — | EP | disclosed |
| CN-114450294-A | Polypeptide with MMP2 inhibitory effect | 大正制药株式会社 | 2022-05-06 | — | — | CN | disclosed |
| US-5674879-A | Compositions including and methods of using conformationally restricted angiotensin II antagonist | G.D. SEARLE & CO. (US) | 1997-10-07 | — | — | US | disclosed |