Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | NLRP3 | Q96P20 | 9/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.33 |
| ▸ | BAD | Q92934 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2050854 | 0.83 | MEN1 (0.43) | MEN1KMT2AACHECA1CA2 | |
| SCHEMBL4888772 | 0.79 | MAPT (0.37) | MEN1KMT2ANLRP3MAPTLMNA | |
| SCHEMBL21586529 | 0.79 | MAPT (0.43) | MEN1KMT2ANLRP3MAPTLMNA | |
| SCHEMBL12057393 | 0.78 | MEN1 (0.61) | MEN1KMT2AACHECA1CA2 | |
| SCHEMBL11819015 | 0.78 | MEN1 (0.47) | MEN1KMT2AACHECA1CA2 | |
| SCHEMBL8742876 | 0.78 | MEN1 (0.40) | MEN1KMT2AACHENLRP3MAPT | |
| SCHEMBL25067262 | 0.77 | MEN1 (0.37) | MEN1KMT2AACHENLRP3MAPT | |
| Dimethylamine SCHEMBL11309528 | 0.77 | MEN1 (0.37) | MEN1KMT2AACHENLRP3ATM | |
| SCHEMBL9810709 | 0.76 | CA1 (0.39) | MEN1KMT2AACHECA1CA2 | |
| SCHEMBL30891958 | 0.75 | MEN1 (0.41) | MEN1KMT2AACHECA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997020802-A1 | INDANE DIMER COMPOUNDS AND THEIR PHARMACEUTICAL USE | VENANTIUS LIMITED (IE) | 1997-06-12 | — | — | WO | disclosed |